Doctors often diagnose tuberous sclerosis complex (TSC) based on the abnormal growths the genetic disease causes in organs around the body. Those overt anatomical structures, however, belie the microscopic and mysterious neurological differences...

Alex experienced his first seizure when he was just six weeks old. His parents later found out that Alex had a genetic disorder called Tuberous Sclerosis, that causes unregulated growths in the brain. It causes seizures — and...

Thousands of individuals have had kidneys removed unnecessarily because doctors misdiagnosed their disease. A new study indicates that approximately one of every five individuals with kidney tumors common in patients with tuberous sclerosis complex,...

Everolimus, a once daily pill that blocks the mTOR pathway, can reduce the size of non-cancerous kidney tumours1 and is licensed today in the UK. Previously embolisation or surgery has been the only option for Tuberous Sclerosis Complex patients...

The European Commission (EC) recently approved Swiss pharmaceutical giant Novartis’ (NVS) Votubia to treat adults suffering from renal angiomyolipoma associated with tuberous sclerosis complex (TSC). The drug can now be used in patients who...

WASHINGTON (MedPage Today) -- The FDA has approved a new indication for everolimus (Afinitor), granting it orphan drug status to treat non-cancerous kidney tumors not requiring immediate surgery in patients with tuberous sclerosis complex.

FRIDAY, April 27 -- Afinitor (everolimus) is the first drug to be approved by the U.S. Food and Drug Administration to treat benign kidney tumors among people with a rare genetic condition called tuberous sclerosis complex (TSC), the agency said...

SAN FRANCISCO (MedPage Today) -- The cancer drug everolimus (Afinitor) appears to shrink a rare type of benign kidney tumor often seen with tuberous sclerosis, researchers found.

Tuberous sclerosis — Comprehensive overview covers symptoms, treatment of this rare tumor-causing genetic disease.

Tuberous sclerosis is a rare genetic disease which results from the mutation in one of two tumor suppressor genes, TSC1 or TSC2. The condition causes non-malignant tumors to grow in the brain and other vital organs throughout the body and skin and...

Tuberous sclerosis complex (TSC) is a multi-system disorder caused by mutations in the TSC1 or TSC2 genes. As illustrated in the signalling diagram on BHDSyndrome.org, TSC1/2 plays an important role...

Novartis (NVS) recently received a boost when its drug Votubia was approved for the treatment of subependymal giant cell astrocytomas (SEGA), a benign brain tumor associated with tuberous sclerosis (TS) in the European Union (EU). For the first...