Amyotrophic Lateral Sclerosis

The Coronavirus Pandemic Disrupted Clinical Trials. A Top Als Researcher Explains How That Helps...

Dr. Merit Cudkowicz is speeding up how treatments for ALS are developed, even during the coronavirus pandemic. Sarah Bastille/Mass General Researchers led by Massachusetts General Hospital are testing several different drugs for ALS at the same...
Related topics: Clinical Trials, Medical Research

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Investigational Drug Stops Toxic Proteins Tied To Neurodegenerative Diseases

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these...
Related topics: Proteins, Dementia

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Sodium Phenylbutyrate-taurursodiol Promising For Als

THURSDAY, Sept. 3, 2020 -- For patients with amyotrophic lateral sclerosis (ALS), function declines more slowly through 24 weeks in those receiving sodium phenylbutyrate-taurursodiol versus placebo, according to a study published in the Sept. 3...
Related topics: Placebo, Medical Research

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Investigational Agent Shows Promise In Als

(MedPage Today) -- An investigational drug known as AMX0035, a proprietary combination of sodium phenylbutyrate and taurursodiol, appeared to slow functional decline in amyotrophic lateral sclerosis (ALS) patients with rapidly advancing disease...

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U.s.a. Facts Of The Day

One in four young adults between the ages of 18 and 24 say they’ve considered suicide in the past month because of the pandemic, according to new CDC data that paints a bleak picture of the nation’s mental health during the crisis. The...
Related topics: Centers For Disease Control And Prevention

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Needles And Vials And Syringes

Thanks to reader Judy R for sending me this article about the behind the scenes work involved in ramping up production of COVID vaccines. While pharmaceutical companies carry out "Operation Warp(ed) Speed" to develop product, run of the mill...
Related topics: Vaccines

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Tunney Lee, Professor Emeritus Of Urban Planning, Dies At 88

Tunney Lee, professor emeritus of urban planning and former head of the MIT Department of Urban Studies and Planning (DUSP), passed away of complications from cancer treatment on July 2 in Boston. He was 88 years old. An architect by training, Lee...
Related topics: Cancer, Oncology

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Scientists Devise New 'bar Code' Method To Identify Critical Cell Types In The Brain

A discovery could pave the way for future studies aimed at developing solutions to ALS and other vexing neuromuscular diseases.
Related topics: Medical Research

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My Friend Was Struck By Als. Here’s How He’s Fighting Back

At 37, Brian Wallach was diagnosed with the fatal disease. So he tapped a lifetime of connections to give help and hope to fellow sufferers—while grappling with his own mortality.

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Column: Nhl Executive Chris Snow Displays Remarkable Resiliency Despite Onset Of Als

Calgary Flames executive Chris Snow was given six to 18 months to live when diagnosed with ALS a year ago. An experimental drug has provided optimism.

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Restoring Nerve-muscle Communication In Als

A new study finds that restoring the protein SV2 in a genetic form of ALS can correct abnormalities in transmission and even prevent cells from dying, providing a new target for future therapies.
Related topics: Medical Research, Proteins, Genetics

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Teeth Predict Als; Apoe4 And Cancer; Parkinson's Drug Approved

]]>(MedPage Today) -- Metal dysregulation in childhood was tied to late-life amyotrophic lateral sclerosis (ALS) using permanent teeth as metal uptake biomarkers. (Annals of Clinical and Translational Neurology) COVID-19 inpatients with...
Related topics: Cancer, Oncology, Parkinson's

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Sugar Turns Brown Algae Into Good Carbon Stores

You may like them or not, but almost everyone knows them: brown algae such as Fucus vesiculosus, commonly known as bladderwrack, grow along the entire German coast. Giant kelp like Macrocystis or Sargassum grow closely together along the coasts but...

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Babies Know When You Imitate Them -- And Like It

Six-month old infants recognize when adults imitate them, and perceive imitators as more friendly, according to a new study. The babies looked and smiled longer at an adult who imitated them, as opposed to when the adult responded in other ways....
Related topics: Medical Research

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Rumor: Next-gen Airpods Could Feature Light Sensors That Would Offer Health-related Tracking...

Per the rumor mill, an upcoming generation of AirPods could feature built-in ambient light sensors (ALS) that could be used for health-related tracking purposes. Industry sources have stated that ALS-equipped next-gen AirPods could be present in...

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'clear Signature' Of Als Found In Children's Teeth

Altered metabolism of zinc, copper, lead, and other metals evident in teeth during childhood and early adolescence are linked with the onset of ALS decades later. Medscape Medical News

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Scientists Identify Gut-brain Connection In Als

Harvard University scientists have identified a new gut-brain connection in the neurodegenerative disease amyotrophic lateral sclerosis, or ALS. The researchers found that in mice with a common ALS genetic mutation, changing the gut microbiome using...
Related topics: Harvard University, Medical Research, Genetics, Microbiome

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Resilience To Als Due To Synaptic Safety Mechanism

A common feature of neurodegenerative diseases such as Alzheimer’s disease and amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) is the progressive loss of synapses – the anatomical sites of communication between brain...
Related topics: Alzheimer's Disease

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How Parenting In A Pandemic Is An Unexpected Opportunity

Being a parent in the middle of a pandemic is not easy. Sheltering in place with canceled daycare, school, and college, while also being a doctor or other healthcare worker, working in high-risk, high-intensity situations, presents many challenges....

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Employees Will Need Their Bosses' Help Getting Through Coronavirus

Paula Caligiuri, Helen De Cieri economy, Americas Here's what you can do. The coronavirus pandemic has forced tens of millions of employees across the U.S. to work from home. While this will save lives by limiting the transmission of COVID-19,...

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