(MedPage Today) -- Final data from the truncated EARLY trial confirmed worse cognition and neuropsychiatric adverse events in preclinical Alzheimer's patients treated with the BACE inhibitor atabecestat, but follow-up testing 6 months after...
Patients with primary progressive aphasia-associated Alzheimer's seem to be more resilient to effects of neurofibrillary tangles in the brain, a new study shows. Medscape Medical News
Related topics: Medical Research
Researchers have used machine learning techniques to predict how proteins, particularly those implicated in neurological diseases, completely change their shapes in a matter of microseconds.
Related topics: Proteins, Medical Research
This winter the novel coronavirus may kill more people than heart disease, cancer, stroke, Alzheimer’s or diabetes
-- Read more on ScientificAmerican.com
Related topics: Cardiovascular Disease, Stroke, Cancer, Oncology, Diabetes
A new study suggests a strong correlation between following the MIND and Mediterranean diets and later onset of Parkinson's disease (PD). While researchers have long known of neuroprotective effects of the MIND diet for diseases like Alzheimer's and...
Related topics: Parkinson's, Medical Research, Diet
This winter the novel coronavirus may kill more people than heart disease, cancer, stroke, Alzheimer’s or diabetes
-- Read more on ScientificAmerican.com
Related topics: Cardiovascular Disease, Stroke, Cancer, Oncology, Diabetes
TUESDAY, Jan. 12, 2021 -- Drug maker Eli Lilly on Monday announced promising results from a small study of an experimental Alzheimer disease drug called donanemab.
The two-year, phase 2 clinical trial included 272 patients with mild-to-moderate...
Related topics: Medical Research, Clinical Trials
(MedPage Today) -- Blood-based biomarkers paralleled the progression of Alzheimer's disease neurodegeneration, a large longitudinal cohort study showed.
Increases of phosphorylated tau at threonine 181 (p-tau181) in blood plasma over time were...
Related topics: Medical Research
Typically characterized as poisonous, corrosive and smelling of rotten eggs, hydrogen sulfide's reputation may soon get a face-lift thanks to researchers. In experiments in mice, researchers have shown the foul-smelling gas may help protect aging...
Related topics: Medical Research
Alabama is the state with the highest number of Alzheimer's deaths compared to the population.
Donanemab, which targets a modified form of amyloid, slowed decline of a composite measure of cognition and function by 32% relative to placebo, topline phase 2 results show. Medscape Medical News
Related topics: Placebo
Jiu-Chiuan Chen
Health,
Here's what we're learning from brain scans.
Alzheimer’s disease is the most common cause of dementia. It slowly destroys memory, thinking and behaviors, and eventually the ability to carry out daily tasks.
As scientists...
Related topics: Dementia
A protein that wreaks havoc in the nerves and heart when it clumps together can prevent the formation of toxic protein clumps associated with Alzheimer's disease, a new study shows. The findings could lead to new treatments for this brain-ravaging...
Related topics: Proteins, Cardiovascular Disease, Medical Research
(MedPage Today) -- The search for a blood test to diagnose Alzheimer's disease has been a long one, and researchers moved closer this year than ever before. In May, MedPage Today reported on an investigational blood assay for tau phosphorylated...
Related topics: Blood Test, Medical Research
Alzheimer’s disease is an incurable form of dementia that affects memory and cognitive functions over time. The condition is the sixth leading cause of death in the United States and the fifth...
Related topics: Dementia
As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes. Scientists now have shown that routine eye imaging can identify changes in the retina that may be...
Related topics: Diabetes
Researchers have been trying to figure out what regulates molecular circadian clocks, in search of new insights into diseases like Alzheimer's, cancer and diabetes. Until now, that research has focused on what is known as clock genes. But new...
Related topics: Medical Research, DNA, Genetics, Cancer, Oncology, Diabetes
In older people with type 1 diabetes, damage to the retina may be linked to memory problems and other cognitive conditions.BOSTON - (December 31, 2020) - As they age, people with diabetes are more likely to develop Alzheimer's disease and other...
Related topics: Diabetes, Type 1 Diabetes
(MedPage Today) -- Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week.
L.A. Hospital Expects to Ration Care
A doctor at a public hospital in Los Angeles County...
Scientists have announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease. Adult onset Leukoencephalopathy with axonal Spheroids and...
Related topics: Medical Research, Genetics, Dementia