Alzheimer's Disease

Should Medicare Pay For Aduhelm?

In June, the FDA approved aducanumab (Aduhelm) to treat patients with Alzheimer’s disease using the agency’s accelerated approval pathway, despite significant concerns about the evidence regarding the drug’s safety and...
Related topics: Medicare, Food And Drug Administration

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Ever Forget Stuff? You May Have Alzheimer’s, Says Maker Of $56k Alzheimer’s Drug

Enlarge / The exterior of the headquarters of biotechnology company Biogen in Cambridge, Massachusetts. (credit: Getty | Boston Globe) Do you ever forget things, like a doctor's appointment or a lunch date? Do you sometimes struggle to think of...
Related topics: Biotechnology

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Health Highlights: July 23, 2021

Here's some of HealthDay's top stories for Friday, July 23: Arguing for & against approval of controversial Alzheimer's drug. The FDA earlier this month gave its OK to the first new Alzheimer's drug in years -- despite its own panel voting...
Related topics: Food And Drug Administration

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Gamma-secretase 'buckles Up' To Reach Its Destination

New research has uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease. In a first step, two dimeric subcomplexes are formed, which independently...
Related topics: Medical Research, Proteins

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Synthesizing Aryl Sulfides From Non-smelling, Non-toxic Compounds

Aryl sulfide, an aromatic compound in which sulfur is attached to an aryl (a functional group derived from an aromatic ring), is found in biologically active materials effective against asthma, Alzheimer's disease, and cancer. As a result, chemists...
Related topics: Asthma, Cancer, Oncology

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The Big Number: Staying Mentally Active As You Grow Older May Delay Onset Of Alzheimer’s By Up To...

Reading books, playing games or doing puzzles added dementia-free time to older people’s lives, researchers say.
Related topics: Dementia, Medical Research

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Spinal Fluid Detects Neurodegeneration, Alzheimer’s In Living Patients

Alzheimer’s disease and related diseases can still only be confirmed in deceased patients’ brains via autopsy. Even so, the development of biomarkers can give patients and their families answers during life: Alzheimer’s disease can be...
Related topics: Autopsies

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The Stakes Of An Fda Probe On New Alzheimer's Drug

(MedPage Today) -- On June 7, the FDA approved a new Alzheimer's drug, aducanumab (Aduhelm). Numerous scientists, clinicians, bioethicists, and policymakers have serious concerns about the drug's efficacy, side effects, and the possible negative...
Related topics: Food And Drug Administration

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Spinal Fluid Biomarkers Detect Neurodegeneration, Alzheimer's Disease In Living Patients

Alzheimer's disease and other forms of neurodegeneration can be identified using a combination of biomarkers in cerebrospinal fluid of living patients, researchers find.
Related topics: Medical Research

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Could Menopausal Hormone Therapy Reduce Women's Odds For Dementia?

TUESDAY, July 20, 2021 -- Women on hormone replacement therapy (HRT) for menopause go on to have a 58% lower risk of Alzheimer's disease and other neurodegenerative conditions, a new study finds. Although the study wasn't designed to prove cause...
Related topics: Menopause, Hormones, Dementia, Medical Research

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Chemists Found An Effective Remedy For "aged" Brain Diseases

Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies.
Related topics: Neurons, Parkinson's

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Science Edition: Alzheimer’s Disease/dementia

Alzheimer’s disease slowly destroys a person’s memory and ability to think. On the Science Edition of Press Conference USA, Dr. Constantine Lyketsos M.D., Professor of Alzheimer’s Research at the Johns Hopkins University School of Medicine,...
Related topics: Dementia, Medical Research

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Got $2,500? Check Out These 3 Alzheimer's Therapy Stocks

Neurodegenerative disorders extract a terrible human toll. In particular, dementia affects more than 44 million people globally with Azheimer's being the most common cause, accounting for 60% to 80% of all cases of dementia. Moreover, dementia is...
Related topics: Dementia

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Expert Panel Says New $56k Alzheimer’s Drug Is Unproven—and Worth $8,400 Max

Enlarge / The exterior of the headquarters of biotechnology company Biogen in Cambridge, Massachusetts. (credit: Getty | Boston Globe) Biogen's new Alzheimer's drug Aduhelm continues to face opposition after its contentious approval by the Food...
Related topics: Biotechnology

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Biogen Falls 8% After 2 Major Hospital Systems Say They Won't Administer Controversial Alzheimer's...

A sign marks a Biogen facility in Cambridge Reuters Shares of Biogen fell as much as 8% after two major hospital systems indicated that they would not administer the controversial Alzheimer's drug, Aduhelm.According to a report from the New...
Related topics: Reuters

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Two Major Health Systems Will Not Administer Controversial Aduhelm

THURSDAY, July 15, 2021 -- Two major U.S. health systems say they will not administer Aduhelm, the controversial new drug for treating Alzheimer disease. The decisions by the Cleveland Clinic and Mount Sinai Health System in New York City are the...

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Think About This: Keeping Your Brain Active May Delay Alzheimer's Dementia 5 Years

Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer's dementia by up to five years.
Related topics: Dementia, Medical Research

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Reading, Puzzles May Delay Alzheimer's By 5 Years: Study

THURSDAY, July 15, 2021 -- An active mind in old age may delay Alzheimer's disease by up to five years, a new study suggests. Activities like reading, writing letters, playing cards or doing puzzles may prolong brain health even for those in their...
Related topics: Medical Research

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Signaling Molecule May Help Prevent Alzheimer's Disease

The main driver of Alzheimer's disease is excessive inflammation in the brain that is triggered by cells called astrocytes and microglia in response to high levels of amyloid beta deposits and tau tangles. New research reveals that a subset of...
Related topics: Medical Research

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Metal-based Molecules Show Promise Against The Build-up Of Alzheimer's Peptides

In lab tests, researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer's disease.
Related topics: Medical Research

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