Alzheimer's Disease

Tau And Pqbp1: Protein Interaction Induces Inflammation In The Brain

Researchers have clarified the relationship between the intracellular receptor PQBP1 and the structural protein Tau, which is dysregulated in neurodegenerative diseases such as Alzheimer's disease. Tau was found to interact with PQBP1 in immune...
Related topics: Proteins, Medical Research

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Could Viagra Help Prevent Alzheimer's?

Researchers from Ohio used a large gene-mapping network to analyze whether more than 1600 FDA-approved drugs could work against Alzheimer's. Sildenafil (Viagra) appeared at the top of the list. WebMD Health News
Related topics: Medical Research, Genetics, Food And Drug Administration

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Study: Antioxidant Flavonol Linked To Lower Risk Of Alzheimer's Dementia

People who eat or drink more foods with the antioxidant flavonol, which is found in nearly all fruits and vegetables as well as tea, may be less likely to develop Alzheimer's dementia years later, according to a study published in the January 29,...
Related topics: Medical Research, Dementia

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Researchers Identify Sildenafil As Candidate Drug For Alzheimer’s Disease

A new study has identified sildenafil -- an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio) -- as a promising drug candidate to help prevent and treat Alzheimer's disease. Researchers determined that...
Related topics: Medical Research, Food And Drug Administration, Erectile Dysfunction, Hypertension

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Scientists Find First In Human Evidence Of How Memories Form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer's disease, and schizophrenia, researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how...
Related topics: Medical Research, Brain Injury, Schizophrenia, Neurons

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Cleveland Clinic Research Identifies Sildenafil As Candidate Drug For Alzheimer's Disease

A new Cleveland Clinic-led study has identified sildenafil - an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Revatio) - as a promising drug candidate to help prevent and treat Alzheimer's disease.
Related topics: Medical Research, Food And Drug Administration, Erectile Dysfunction, Hypertension

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Elevated Heart Rate Linked To Increased Risk Of Dementia

Having an elevated resting heart rate in old age may be an independent risk factor of dementia, according to a study at Karolinska Institutet in Sweden published in the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s...
Related topics: Dementia, Medical Research

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Scientists Discover Potential Cause Of Alzheimer’s Disease

In people with brain buildups, a key but difficult-to-detect difference in the form of tau protein allows scientists to distinguish people showing no outward signs of dementia from those who do.
Related topics: Medical Research, Proteins, Dementia

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How Exercise May Support The Aging Brain

Simple activities like walking boost immune cells in the brain that may help to keep memory sharp and even ward off Alzheimer’s disease.

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Could Roche Put A Crinkle In Biogen's Alzheimer's Drug Launch?

Roche (OTC: RHHBY) is considering a launch of its Alzheimer's disease drug, gantenerumab, at a price that could undercut competition from Biogen's (NASDAQ: BIIB) Aduhelm. In this Motley Fool Live video recorded on Nov. 15, Motley Fool contributors...
Related topics: Nasdaq, Health Videos

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Blood Test May Detect Preclinical Alzheimer's Years In Advance

A new blood test that identifies a variant of the protein P53 appears to predict Alzheimer's disease progression up to 6 years in advance of a clinical diagnosis, early research suggests. Medscape Medical News
Related topics: Blood Test, Proteins, Medical Research

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Physical Activity May Improve Alzheimer’s Outcomes By Lowering Brain Inflammation

No one will disagree that an active lifestyle is good for you, but it remains unclear how physical activity improves brain health, particularly in Alzheimer’s disease. The benefits may come about through decreased immune cell activation, according...

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The Institute For Molecular Medicine Has Received A Total $7.7m From Nih To Develop A...

The Institute for Molecular Medicine will advance the manufacturing of Duvax for the first clinical trials of a dual vaccine for Alzheimer's disease to begin in 2023
Related topics: Vaccines, Clinical Trials

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Concerns Grow Over Safety Of Aduhelm After Death Of Patient Who Got The Drug

Newly published safety data shows that 41 percent of patients in key clinical trials of the Alzheimer’s drug experienced brain bleeding or swelling, though many cases were asymptomatic.
Related topics: Clinical Trials

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Right Off The Bats

Among the many devastating impacts of Alzheimer's disease and other types of dementia is the risk that patients will wander and become lost. Indeed, according to the Alzheimer's Association, six in 10 people with the disease will wander at least...
Related topics: Dementia

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As Gene-editing Moves Mainstream, A Pioneer In The Field Is Testing Whether It Could Prevent...

Beam Therapeutics cofounder David Liu.Jessica Rinaldi/The Boston Globe via Getty Images Scientist and biotech cofounder David Liu is one of the pioneers of drugs that can edit DNA. His lab is developing therapy that could prevent Alzheimer's by...
Related topics: Genetics, DNA

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A Personal Glimpse At Living With Early-onset Alzheimer’s Disease

Two people share their stories of confusion and loss as well as helpful tips on how to navigate the world after an unexpected dementia diagnosis.
Related topics: Dementia

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Let Ethics Guide Aducanumab Prescribing, Aan Says

(MedPage Today) -- With incomplete data to guide aducanumab (Aduhelm) prescribing, neurologists face ethical challenges and will be guided best by established principles to counsel people with Alzheimer's disease and their families, said a new...

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We Got A Look At The 16-slide Presentation Medarrive Used To Raise $25 Million

Hello,Welcome to Insider Healthcare. I'm healthcare editor Leah Rosenbaum, and today in healthcare news:Home healthcare company MedArrive shares its Series A pitch deck;Alzheimer's drug company Cassava Sciences under government...

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New Approach Provides Potential Vaccine And Treatment For Alzheimer’s

A promising new approach to potentially treat Alzheimer's disease -- and also vaccinate against it -- has been developed by a team of scientists.
Related topics: Vaccines

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