Antidepressants

Pressing Reset On Depression

Transcranial magnetic stimulation offers hope for antidepressant-resistant psychiatric disorders at UC San Diego Health.
Related topics: Depression

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Review Reports Improved Transparency In Antidepressant Drug Trials

New research suggests manufacturers of newly developed antidepressant drugs have become more forthcoming about clinical trials that don't pan out. While the new findings are encouraging, they still hint at a fundamental shortcoming in medicine: A...
Related topics: Depression, Clinical Trials, Medical Research

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Antidepressants: Is Less More?

A new review suggests antidepressants' efficacy is questionable, leading researchers to recommend that when these agents are prescribed, it should be for shorter periods. Medscape Medical News
Related topics: Depression, Medical Research

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Novel Antidepressant Shows Promise As Add-on Therapy

A novel NMDAR antagonist provides rapid and sustained antidepressant effects in patients with major depression ― without the dissociative effects common with ketamine, a new phase 2a study suggests. Medscape Medical News
Related topics: Depression, Medical Research

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Many Common Medications Can Raise Your Blood Pressure

Popular pain relievers and antidepressants, as well as alcohol and herbal supplements, are among the many substances that can contribute to hypertension.
Related topics: Hypertension, Blood Pressure, Depression, Alcohol

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Do Antidepressants Change Your Personality?

The answer is more nuanced than you might think.
Related topics: Depression

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Anxiety Drugs And Antidepressants Trigger Post-surgery Delirium, Study Finds

A new study finds that older people taking a drug used to treat anxiety and insomnia -- nitrazepam -- as well as those on antidepressants, are twice as likely to suffer postoperative delirium after hip and knee surgery.
Related topics: Anxiety, Depression, Medical Research, Insomnia

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Covid Patients On Ssri Antidepressants Are Less Likely To Die, Ucsf-stanford Study Finds

A large analysis of health records from 87 health care centers across the United States found that people taking a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine, were significantly less...
Related topics: Selective Serotonin Reuptake Inhibitors, Depression, Medical Research

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Utsw-led Research Identifies New Imaging Biomarkers That Predict Antidepressant Response

The outcome predictive models were developed in part using data from a large multi-center National Institute of Mental Health-funded study and published in the journal Biological Psychiatry. The findings provide strong evidence that the current...
Related topics: Medical Research, Depression

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Deep Brain Stimulation Surgery For Treatment-resistant Depression: Brain Rhythm Changes Fast

Findings provide a putative physiological biomarker of brain state changes that can predict early antidepressant effects.
Related topics: Depression

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Antidepressant Use In Pregnancy Linked To Worse Math Test Scores In Kids

(MedPage Today) -- Children whose mothers used antidepressants during pregnancy performed worse on math exams, a retrospective study from Denmark found. Average test scores in mathematics were 52.1 among kids exposed to antidepressants in utero...
Related topics: Depression, Medical Research

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Novel Oral Antidepressant Shows Rapid Symptom Improvement

(MedPage Today) -- A 2-week oral treatment for major depressive disorder was both safe and effective, according to the phase III WATERFALL study. Compared with placebo, adults treated with zuranolone, an investigational neuroactive steroid and...
Related topics: Depression, Medical Research, Placebo

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Common Antidepressant Slashes Risk Of Covid Death

Fluvoxamine is both inexpensive and highly effective at preventing mild COVID-19 from turning severe -- Read more on ScientificAmerican.com
Related topics: Depression

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The New Fluvoxamine Results Have Been Published

The core work, led by Edward J. Mills, is now refereed and published in Lancet.  From the New York Times: A large clinical trial has found that a common and inexpensive antidepressant lowered the odds that high-risk Covid-19 patients would be...
Related topics: The Lancet, Clinical Trials, Depression

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Antidepressant Found To Reduce Covid-19 Hospitalizations: Study

An affordable antidepressant has been found in a clinical trial to reduce the risk of hospitalization in high-risk adults with recently diagnosed COVID-19, according to a study published in The Lancet Global Health.The drug, known as fluvoxamine,...
Related topics: Depression, Medical Research, Clinical Trials, The Lancet

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Cat’s Meow: Robotic Pet Boosts Mood, Behavior And Cognition In Adults With Dementia

Individuals with Alzheimer’s disease or related dementias (ADRD) often experience behavioral and psychological symptoms such as depression, aggression and anxiety. Frequently, these symptoms are treated with antipsychotics, antidepressants and...
Related topics: Robots, Dementia, Alzheimer's Disease, Psychology, Depression, Anxiety

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Common Antidepressant Should No Longer Be Used To Treat People With Dementia

A drug used to treat agitation in people with dementia is no more effective than a placebo, and might even increase mortality, according to a new study. The research has shown that antidepressant mirtazapine offered no improvement in agitation for...
Related topics: Depression, Dementia, Placebo, Medical Research

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Sleep-cognition Link; Parkinson's Risk After Infection; N-of-1 Neurology Trials

(MedPage Today) -- Both short and long sleepers experienced greater cognitive decline than people who hit a sweet spot of total sleep time, even in early Alzheimer's disease. (Brain) The antidepressant drug mirtazapine (Remeron) was no better...
Related topics: Parkinson's, Alzheimer's Disease, Depression

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Helping Those With Depression Pick An Antidepressant

Although antidepressants are one of the most frequently taken medications in the United States (11% of the population takes antidepressants)[i] [ii], 60% of depressed patients do not benefit from their first antidepressant.[iii] The sales of...
Related topics: Depression

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Afghans Are Self-medicating With Antidepressants Bought On The Black Market As Despair At Life...

Oliver Weiken/Getty Images; Marianne Ayala/Insider Afghans are traumatized and depressed, and experts say the mental health system is ill-equipped to help them. Sources described how desperate Afghans are self-medicating with antidepressants and...
Related topics: Depression

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