Clinical Trials

Medical News Today: Ending Hiv Transmission: What Is The Impact Of Giving Out Free Self-tests?

A randomized clinical trial evaluated the effects of providing free HIV self-tests in a high-risk population and the results are in.
Related topics: HIV, Virus

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Roswell Park Spinoff Company Advances Toward New Clinical Trial For Brain Cancer Immunotherapy...

The inventors of a cancer immunotherapy developed at Roswell Park Comprehensive Cancer Center have announced a major step forward with that therapy, SurVaxM -- a multimillion-dollar licensing deal that will help enable large, randomized clinical...
Related topics: Brain Tumors, Cancer, Oncology

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Silencing Novel Target Genes: A New Strategy For Lipid Lowering

Following in the footsteps of inclisiran, two lipid-lowering therapies based on silencing specific genes involved in lipid metabolism showed promising preliminary results in initial clinical trials. Medscape Medical News
Related topics: Genetics

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India Develops World's First Male Contraceptive Injection

New Delhi (Sputnik): The apex medical council of India has successfully completed the clinical trial of the world’s first injectable male contraceptive which now requires regulatory approvals from the Drug Controller General of India (DCGI) before...

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Prescription Fish Oil Drug Vascepa Slows Clogging In Arteries

MONDAY, Nov. 18, 2019 -- Prescription-strength fish oil slows the development of artery-clogging plaques, according to early results from an ongoing clinical trial. Icosapent ethyl -- a purified fish oil drug sold under the brand name Vascepa --...

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One-two Punch Drug Combination Offers Hope For Pancreatic Cancer Therapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice--supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and...
Related topics: Pancreatic Cancer, Cancer, Oncology, Medical Research

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One-two Punch Drug Combination Offers Hope For Pancreatic Cancer Therapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice--supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and...
Related topics: Pancreatic Cancer, Cancer, Oncology, Medical Research

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Teens With Heart Disease Improve Exercise Capacity In Large Clinical Trial

The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe, congenital single-ventricle heart defects. A study leader says the...
Related topics: Cardiovascular Disease, Cardiology, Medical Research

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Controlled Human Infection Method: ‘unethical’ Clinical Trials Of Vaccines Pose Threat To Human...

In the USA, we might call this "The Tuskegee method."  As I watched Vaxxed II last week, it was the Gardasil stories that affected me the strongest. The fact that the placebo in testing was not by even the lowest scientific standards a placebo...
Related topics: Vaccines, Placebo

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Here's Why Restorbio Fell Over 83% Today

Shares of resTORbio (NASDAQ: TORC) fell over 83% today after the company reported that its lead drug candidate, RTB101, failed a late-stage clinical trial evaluating its potential to prevent respiratory illness in adults over 65. The company has...
Related topics: Nasdaq

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Clinical Trials Of Russian Medicine For Gluten Intolerance Slated To Start In 2020

The first phase of clinical trials of a drug to treat gluten intolerance, developed by scientists from Sechenov University, is planned to be carried out in 2020. The drug itself may appear on the market three to four years after testing.
Related topics: Medical Research

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Crc Trial Misses Pfs Goal With Active Regimen

(MedPage Today) -- NATIONAL HARBOR, Md. -- A first-line multidrug combination failed to meet a progression-free survival (PFS) primary endpoint for metastatic colorectal cancer (mCRC) despite eye-opening clinical activity, according to a study...
Related topics: Colon Cancer, Colorectal Cancer, Cancer, Oncology, Medical Research

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Microparticles Could Help Fight Malnutrition

Researchers have now developed a new way to fortify staple foods with these micronutrients by encapsulating them in a biocompatible polymer that prevents the nutrients from being degraded during storage or cooking. In a small clinical trial, they...
Related topics: Medical Research

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For Older Adults, New Hepatitis C Treatments Are Safe And Effective, Study Suggests

Thankfully, newer treatments known as interferon-free direct-acting antivirals offer a promising approach to addressing hepatitis C. These medications offer cure rates of more than 90 percent in clinical trials and in real life, but they haven't...
Related topics: Hepatitis, Hepatitis C, Medical Research

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Here’s Why Fibrogen’s Stock Popped Friday

On Nov. 8, FibroGen (NASDAQ: FGEN) and its partner AstraZeneca (NYSE: AZN) reported safety and efficacy data from a pooled analysis of six large phase 3 clinical trials with roxadustat, a drug aimed at treating anemia in patients with chronic...
Related topics: Nasdaq, Astrazeneca, Anemia

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Opioids Won't Help Arthritis Patients Long-term: Study

SATURDAY, Nov. 9, 2019 -- Opioid painkillers may temporarily ease the discomfort of arthritis, but they have no clear lasting benefit, a research review finds. In an analysis of 23 clinical trials, researchers found that, on average, opioid...
Related topics: Arthritis, Medical Research, Painkillers

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Machine Learning Shows No Difference In Angina Symptoms Between Men And Women

The symptoms of angina — the pain that occurs in coronary artery disease — do not differ substantially between men and women, according to the results of an unusual new clinical trial led by MIT researchers. The findings could help overturn the...
Related topics: Angina Pectoris, Medical Research

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Media Alert: American Society Of Nephrology Kidney Week Press Briefing

Briefing will feature presentations of High-Impact Clinical Trials. Dr. Pascale Lane and Dr. Kelly Hyndman will moderate and provide context and expert commentary on the science presented.

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In-brain Electrodes Are The Latest Weapon Against Opioid Addiction

Researchers at the West Virginia University Rockefeller Neuroscience Institute (RNI) and West Virginia University Medicine are conducting the first clinical trial in the US that uses deep brain stimulation to treat opioid addiction. The procedure...
Related topics: Medical Research

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Teprotumumab Improves Bulging, Qol, In Thyroid Eye Disease

The pooled results of phase 2 and 3 clinical trials could pave the way for first approved drug for thyroid eye disease. Medscape Medical News

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