Clinical Trials

New Anti-pd-1 Drug Active In Advanced Colon Cancer

(MedPage Today) -- Almost 40% of progressive, advanced gastrointestinal (GI) tumors with mismatch repair deficiency (dMMR) responded to the investigational anti-PD-1 agent dostarlimab, according to a preliminary clinical trial. Overall, 38.7...
Related topics: Colon Cancer, Cancer, Oncology

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Combination Treatment For Methamphetamine Use Disorder Shows Promise In Nih Study

A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial. The findings...
Related topics: Medical Research, Placebo

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Johnson & Johnson's One-dose Covid-19 Vaccine Promising In Early Trial

WEDNESDAY, Jan. 13, 2021 -- A single-shot COVID-19 vaccine from Johnson & Johnson has shown very strong results in early clinical trials, potentially providing a significant boost to U.S. vaccination efforts. The vaccine produced an immune...
Related topics: Vaccines

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This Common Drug Might Save People With Covid-19

A new study suggests that the anti-cholesterol drug Fenofibrate, also known as Ticor, can help treat coronavirus patients. In lab testing with the drug, the coronavirus completely went away after just five days. Clinical trials with Fenofibrate...
Related topics: Medical Research, Cholesterol

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Combination Treatment For Methamphetamine Use Disorder Shows Promise

A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial. The findings...
Related topics: Placebo

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Johnson & Johnson's One-dose Covid Vaccine Promising In Early Trial

WEDNESDAY, Jan. 13, 2021 -- A single-shot COVID-19 vaccine from Johnson & Johnson has shown very strong results in early clinical trials, potentially providing a significant boost to U.S. vaccination efforts. The vaccine produced an immune...
Related topics: Vaccines

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Monoclonal Antibody Induces Weight Loss In Type 2 Diabetes

(MedPage Today) -- A human monoclonal antibody that failed in treating muscle-wasting disease may find new life as an anti-obesity and anti-diabetes drug, according to results of a phase II clinical trial. In 75 overweight or obese patients with...
Related topics: Type 2 Diabetes, Diabetes, Obesity

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Florida Doctor Pleads Guilty To Faking Clinical Trial Data

(MedPage Today) -- A Florida doctor has pleaded guilty to falsifying clinical trial data for an asthma medication that was being studied in young children, the U.S. Department of Justice announced. Yvelice Villaman-Bencosme, MD, admitted that...
Related topics: Asthma

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Dr. Fauci Discusses The Only Side Effect He Felt From His Coronavirus Vaccine

Coronavirus vaccines from Pfizer and Moderna were proven to be safe in clinical trials and rarely caused severe side effects. Commenting on his own experience, Dr. Fauci said that the only side effect he experienced was a sore arm. Side effects from...
Related topics: Vaccines, Pfizer

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Medicine Must Create Inclusive Clinical Trials [podcast]

“Researchers should make clinical trials more accessible by providing patients with simple explanations of studies at a variety of locations, including community clinics and medical centers. Increased flexibility regarding transportation and...
Related topics: Podcasts, Medical Research

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Brazilian Health Officials: Chinese Covid-19 Vaccine Is 78 Percent Effective

A COVID-19 vaccine developed by a Chinese company is effective, Brazilian officials said Thursday, announcing results of a large clinical trial. Brazil’s Butantan Institute tested the vaccine in more than 12,000 health workers in phase three...
Related topics: Vaccines

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Wednesday Assorted Links

1. How to run a simple and fairly quick clinical trial on First Doses First.  It is funny how you do not hear the critics suggest the merits of further investigation. 2. “American Chess Magazine Releases Their List of the Top 1 Shows of...

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Could Umbilical Cord Stem Cells Be A Lifesaver Against Severe Covid-19?

TUESDAY, Jan. 5, 2021 -- Stem cells derived from a baby's umbilical cord can help save the lives of the sickest COVID-19 patients, results from a small new clinical trial suggest. Severely ill COVID patients who received two intravenous doses of...
Related topics: Umbilical Cord, Stem Cells

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Anticov Treatment Clinical Trial Crucial For Africa

Only a united Africa can defeat COVID-19. Credit: WHOBy Sam OtienoNAIROBI, Kenya, Jan 5 2021 (IPS) The ANTICOV COVID-19 clinical trial, aimed at identifying treatments that prevent mild cases from progressing to severe forms of the disease, is...

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Here's Why Drugmakers Face A Dilemma Now That 2 Vaccines Are Rolling Out

The authorization of two coronavirus vaccines by the Food and Drug Administration makes it more complicated for other drug companies to get their vaccines through the clinical trial process. In this video from Motley Fool Live, recorded on Dec. 21,...
Related topics: Vaccines, Food And Drug Administration, Health Videos

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Liso-cel Shows Promising Clinical Activity And Safety In Cll

(MedPage Today) -- At the American Society of Hematology (ASH) virtual meeting, a number of important chronic lymphocytic leukemia (CLL) trial updates were presented. MedPage Today brought together three expert leaders in their field: Moderator...
Related topics: Hematology, Leukemia

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"diversity" Nonsense Cost Tens Of Thousands Of Lives

CNBC in September (but I just saw this today): "One of the developers in the lead for a vaccine to prevent Covid-19, is slowing enrollment slightly in its large clinical trial to ensure it has sufficient representation of minorities most at risk for...
Related topics: Cnbc, Vaccines

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Transfusions With Higher Red Blood Cell Levels Do Not Improve Preterm Baby Outcomes

A randomized clinical trial is the largest study to-date to compare thresholds for blood transfusions in premature babies, offers guidance for health care providers.
Related topics: Medical Research

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Finding Benefits In Cancer; Trial Slowdowns; Metastatic Breast Ca Surgery

(MedPage Today) -- A majority of patients with colorectal cancer found at least one benefit from their diagnosis. (Fox Chase Cancer Center) Half of disruptions in ongoing clinical trials resulted from slow patient enrollment....
Related topics: Breast Cancer, Cancer, Colon Cancer, Colorectal Cancer, Oncology

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Brazilian Uniao Quimica Seeks To Hold Clinical Trials Of Sputnik V, Authorities Say

BUENOS AIRES (Sputnik) - The Brazilian Uniao Quimica pharmaceutical company, which has an agreement with Russia on the production of the Sputnik V vaccine in Brazil, has submitted an application with the national health regulatory agency, Anvisa, to...
Related topics: Vaccines

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