Clinical Trials

Study Finds Need For Better Inclusion Of Patients From Racial Minority Groups In Radiation Therapy...

A new study finds that the racial composition of clinical trials involving radiation therapy does not match that of the U.S. population. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.
Related topics: Medical Research, American Society Of Clinical Oncology, Cancer, Oncology

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Nih Ends Clinical Trial Of Eli Lily's Coronavirus Antibody Therapy Candidate

A phase 3 clinical trial of a potential COVID-19 antibody therapy developed by Eli Lilly (NYSE: LLY) has been halted permanently, the company reported Monday night. No additional eligible participants will be dosed with LY-CoV555, also known as...

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Aspirin: A New Tool To Fight Coronavirus?

Ethen Kim Lieser Coronavirus, “This is a critical finding that needs to be confirmed through a randomized clinical trial,” the study’s lead author Dr. Jonathan Chow said in a news release. “If our finding is confirmed, it would make...
Related topics: Aspirin, Medical Research

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How To Conduct Clinical Trials While Releasing A Vaccine

There are many ways to conduct clinical trials while releasing a vaccine—indeed, we can make the clinical trials better by randomizing a phased release. Suppose we decide health care and transit workers should be vaccinated first. No...
Related topics: Vaccines

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Radiosurgery Reduces Cognitive Decline Without Compromising Survival For Patients With 4+ Brain...

Results of a new randomized phase III trial suggest that stereotactic radiosurgery (SRS) should replace whole brain radiation therapy (WBRT) as the standard of care for patients with four or more brain metastases. Results from the clinical trial...

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Uk Health Minister Dispels Rumour Hospital Trust Staff To Receive Astrazeneca Covid Vaccine Soon

Clinical trials of the anti-coronavirus vaccine developed by AstraZeneca pharmaceutical company in partnership with Oxford University were previously halted in the UK after one of the British participants contracted an “unexplained illness”, ...
Related topics: Astrazeneca, Vaccines, Medical Research

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Targeted Inhibitor Of Mutated Kras Gene Shows Promise In Early Trial For Lung, Bowel, And Other...

A novel agent that targets a mutated form of the KRAS gene - the most commonly altered oncogene in human cancers and one long considered "undruggable" - shrank tumors in most patients in a clinical trial with manageable side effects, researchers...
Related topics: Genetics, Lung Cancer, Cancer, Oncology, Medical Research

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Vaccine Trials Resume After Pauses By Astrazeneca And Johnson & Johnson

Two major clinical trials for experimental Covid-19 vaccines got back on track in the United States Friday — providing a glimmer of hope as the number of cases skyrocket across the country. Covid-19 has now killed more than 223,000 Americans,...
Related topics: Vaccines, Astrazeneca

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Woman Recovering From Covid-19 Shares Experience As Monoclonal Antibody Clinical Trial Participant

When Christina Loville tested positive for the coronavirus, she was terrified. She decided to channel her fear into researching COVID-19 treatments, where she discovered a local clinical trial led by experts at The University of Texas Health Science...
Related topics: Medical Research

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Clinical Trial Shows Experimental Drug Safely Slows Progression Of Diabetic Kidney Disease

Patients with diabetic kidney disease can potentially be treated with a new investigational medication that may slow the progress of their illness without harmful side effects to their hearts, according to the results of a global clinical trial...
Related topics: Diabetes, Kidney Disease

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Moderna Vax Trial Full; Azar Denies Hahn Rift; Mitch Mcconnell's Handgate

(MedPage Today) -- Note that some links may require registration or subscription. Thursday marked completion of enrollment in Moderna's U.S. vaccine clinical trial: 30,000 participants have received their first shot. (The Washington Post) And...
Related topics: Vaccines

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Blood Of Recovered Covid-19 Patients Shows Little Benefit As Treatment, Study Finds

Using blood of recovered COVID-19 patients, the so-called convalescent plasma, as a potential treatment is of little benefit in helping hospitalized patients fight off the infection, according to results of a clinical trial in India.Published in the...
Related topics: Medical Research

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Fda Advisers Grapple With Covid Vaccine Questions

Members of an expert panel advising the Food and Drug Administration (FDA) on coronavirus vaccines on Thursday argued against ending clinical trials even after the first vaccine becomes available.There is no vaccine for COVID-19 for the panel to...
Related topics: Food And Drug Administration, Vaccines

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Toward A New Staging System For Prostate Cancer, And Why It Matters

The development and validation of a staging system for non-metastatic prostate cancer could help doctors and patients assess treatment options, as well as improve clinical trials.
Related topics: Prostate Cancer, Cancer, Oncology

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Dr Reddy’s Suffers Cyber Attack Days After Getting Approval For Russia's Sputnik V Trials In India

The Russian Direct Investment Fund (RDIF) and pharmaceutical company Dr Reddy’s have been conducting late-stage clinical trials in India for the Sputnik V coronavirus vaccine since getting renewed approval by the drug controller in New Delhi. Dr...
Related topics: Vaccines

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Who's In Line For Covid-19 Vaccines?

The COVID-19 vaccines are coming.The question is, who gets them first? And who is next in line?Two companies say that by late November, they expect to have initial results from clinical trials showing whether their vaccines are safe and effective....
Related topics: Vaccines

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Brazil Healthcare Regulator Says Patient In Astrazeneca Coronavirus Vaccine Trial Dies

Anvisa, Brazil's healthcare regulator, said Wednesday that it was told a patient in a late-stage clinical trial of AstraZeneca's (NYSE: AZN) COVID-19 vaccine candidate has died. Citing medical confidentiality, it did not provide any details about...
Related topics: Astrazeneca, Vaccines

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Bad Sad Season Coming; Oxycontin Maker Cops Plea

(MedPage Today) -- A meta-analysis of 39 randomized clinical trials concluded pharmacotherapy plus manualized psychotherapy -- cognitive behavioral therapy, family/conjoint therapy, interpersonal therapy, or psychoeducational therapy -- was...
Related topics: Police

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Plant-grown Vaccines: The Next Step In Medicine?

Canadian biotech company Medicago is growing a vaccine candidate in Nicotiana benthamiana.An Australian relative to tobacco, plant-based vaccines could be cheaper and more reliable than current methods.Medicago just completed phase 3 clinical trials...
Related topics: Vaccines, Smoking

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Trial To Deliberately Infect People With Coronavirus Draws Mixed Reaction

Enlarge / Woman receives an experimental COVID-19 vaccine at the University of Massachusetts Medical School in Worcester, MA, on September 04, 2020, as part of a clinical trial. (credit: Getty | Boston Globe) Researchers in the United Kingdom plan...
Related topics: Vaccines, Medical Research

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