Enzymes

Study Finds Promising Therapeutic Target For Colitis

An international research group, led by Jamey Marth, Ph.D., a professor at Sanford Burnham Prebys, has shown that the Neuraminidase 3 (Neu3) enzyme is responsible for the onset and progression of colitis--a chronic digestive disease caused by...
Related topics: Medical Research

Read More →

Converting P450 Peroxygenase Into Peroxidase Via Mechanism-guided Protein Engineering

Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging.
Related topics: Proteins, Biofuel

Read More →

Research That Shines Light On How Cells Recover From Threats May Lead To New Insights Into...

Brian Andrew Maxwell Health, Scientists still need to identify which enzymes are responsible for putting the ubiquitin tag on proteins during stress in the first place. The big idea Our bodies contain a special protein tag that plays a role in...
Related topics: Medical Research, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Proteins, Stress

Read More →

Scientists Blueprint Bacterial Enzyme Believed To 'stealthily' Suppress Immune Response

Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a 'stealthy' role in the progression of infection by reducing the immune response. Blueprints such as these allow drug...
Related topics: Bacteria

Read More →

Enzyme From Fungi Shows Molecules Which Way To Turn

A small fungal enzyme could play a significant role in simplifying the development and manufacture of drugs, according to Rice University scientists.
Related topics: Medical Research

Read More →

Unraveling The Mechanisms That Create The Individualized Metabolism In Leukemia

Lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells. Cancer cells have a unique ability to metabolize substances differently from...
Related topics: Leukemia, Genetics, Cancer, Oncology

Read More →

Novel Strategy For Natural Product Biosynthesis

Researchers discover enzyme prototype for formation of ecologically and pharmaceutically important tropone compounds.
Related topics: Medical Research

Read More →

A Promising Pathway To New Cancer Treatments

Using Argonne National Laboratory's Advanced Photon Source, researchers have determined the structure of an enzyme that plays a key role in the spread of cancer cells.
Related topics: Cancer, Oncology, Medical Research

Read More →

Hard-working Enzyme Keeps Immune Cells In Line

Researchers at La Jolla Institute for Immunology (LJI) have shed light on a process in immune cells that may explain why some people develop cardiovascular diseases. Their research, published recently in Genome Biology, shows the key role that TET...
Related topics: Medical Research, Cardiovascular Disease, Cardiology, Genetics

Read More →

Most ‘compostable’ Plastics Are Anything But. Enter Polymer-eating Enzymes.

Researchers at the University of Berkeley have created plastics that degrade within weeks – all it takes is heat and water. The technology works by adding polymer-eating enzymes to the plastics, which then lump together and break down the...
Related topics: Medical Research

Read More →

These Bottles Are The First Made From Plastic Recycled By Enzymes

The enzymes break down plastic to the molecular level, making it easier to use different kinds of plastics to make new bottles. Inside landfills, researchers have found rare but naturally occurring enzymes that break down plastic. By tweaking one of...
Related topics: Medical Research

Read More →

The Origin Of Sars-cov-2

SARS-CoV-2 has a very unusual feature: it is surprisingly good at infecting a particular type of cell that has what is known as an angiotensin-converting enzyme 2 receptor. Some other animals have ACE2 receptors, but SARS-CoV-2 works much better in...

Read More →

Detoxifiers From The Landfill

Bacteria from an Indian landfill could help eliminate contaminated chemicals. The focus is on pesticides such as lindane or brominated flame retardants, which accumulate in nature and in food chains. Researchers used these bacteria to generate...
Related topics: Bacteria, Medical Research

Read More →

How Cells "read" Artificial Ingredients Tossed Into Genetic Recipe

UC San Diego School of Medicine researchers discovered that the enzyme RNA polymerase II recognizes and transcribes artificially added base pairs in genetic code, a new insight that could help advance the development of new vaccines and medicines.
Related topics: Genetics, Medical Research, Vaccines

Read More →

Self-healing Concrete Could Multiply Lifespans Of Structures

Researchers at Worcester Polytechnic Institute (WPI) are using an enzyme found in red blood cells to create self-healing concrete that is four times more durable than traditional concrete, extending the life of concrete-based structures and...
Related topics: Medical Research

Read More →

Bees Have A New, Lifesaving ‘vaccine,’ Too

Feeding them an enzyme can protect them from pesticides and could change the horrifying trajectory of declining bee populations. Fifteen years after beekeepers first started reporting mass die-offs of bees, it’s still common for an average...
Related topics: Vaccines

Read More →

Sars-cov-2 Protease Cuts Human Proteins; Possible Link To Covid-19 Symptoms

The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. Now, researchers have found...
Related topics: Proteins, Medical Research

Read More →

Drug Lynparza Could Help Fight Some Early-stage Breast Cancers

FRIDAY, June 4, 2021 -- A twice-daily pill can dramatically reduce the risk of breast cancer recurrence in women who are genetically prone to the disease, researchers report. The pill — olaparib (Lynparza) — works by blocking a natural enzyme...
Related topics: Breast Cancer, Cancer, Oncology, Genetics, Medical Research

Read More →

Scientists Identify Protein That Activates Plant Response To Nitrogen Deficiency

Researchers have identified a plant enzyme that is key to activating a nitrate uptake mechanism in response to nitrogen starvation. This finding explains how plants meet their needs in challenging environments, opening doors to improving agriculture...
Related topics: Proteins, Medical Research

Read More →

Glioblastoma Study Discovers Protective Role Of Metabolic Enzyme, Revealing A Novel Therapeutic...

MD Anderson researchers have discovered a new role for the metabolic enzyme, MCAD, in glioblastoma. The enzyme prevents toxic fatty acid accumulation, in addition to its normal role in energy production, and targeting MCAD led to irreversible damage...
Related topics: Glioblastoma, Medical Research

Read More →
What is noozilla?
Noozilla is an independent news aggregation service with a categorization engine that categorizes millions of news stories by subject.