Enzymes

While Promoting Diseases Like Cancer, These Enzymes Also Cannibalize Each Other

In diseases like cancer, atherosclerosis, and sickle cell anemia, cathepsins promote their propagation. Drug trials to inhibit these enzymes have failed due to baffling side effects. Now a new study examines cathepsins in systems to remove some of...
Related topics: Cancer, Oncology, Atherosclerosis, Anemia, Medical Research

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Researchers Completely Re-engineer Yeast To Make More Biofuel

Enlarge / Colonies of genetically modified yeast. (credit: Conor Lawless) A little while ago, we covered the idea of using photovoltaic materials to drive enzymatic reactions in order to produce specific chemicals. The concept is being considered...
Related topics: Medical Research, Biofuel, Genetics

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Leviathan Polymer Brush Made With E. Coli Holds Bacteria At Bay

A lab goof with an enzyme taken from bacteria has led to the creation of the Leviathan of polymer brushes, emerging biocompatible materials with the potential to repel infectious bacteria.
Related topics: Bacteria

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A New Model Of Metabolism Draws From Thermodynamics And 'omics'

All living things are made of carbon, and sugars like glucose are a very common source of it. Consequently, most cells are good at eating sugars, using enzymes to digest them through a series of chemical reactions that transform the initial sugar...

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A Response Key For Survival Of Mycoplasma Genitalium In The Urogenital Tract Uncovered

Metals (iron, zinc, nickel, cobalt, etc.) participate in numerous enzymatic reactions and are essential nutrients for bacteria. Inside our organism, but these metals are scarcely available, because they are bound to proteins which preserve and...
Related topics: Bacteria, Proteins

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Predatory Lacewings Do Not Care Whether Their Prey Detoxifies Plant Defenses Or Not

A new study shows that herbivores and their predators have evolved efficient strategies to deal with toxic plant secondary metabolites. Caterpillars of the diamondback moth deploy a specific gut enzyme to render the toxic substances of their host...
Related topics: Medical Research

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New Therapeutic Strategy For Chemotherapy Resistance In Ovarian Cancer

A Wistar study demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment.
Related topics: Chemotherapy, Cancer, Ovarian Cancer, Oncology, Medical Research, Stem Cells

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Virus Multiplication In 3-d

For viruses to multiply, they usually need the support of the cells they infect. In many cases, only in their host's nucleus can they find the machines, enzymes and building blocks with which they can multiply their genetic material before infecting...
Related topics: Virus, Virology, Genetics

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Medicare For All Advocates Are In For A Rude Awakening

Migrating to the U.S. as an international medical graduate, I was shocked by the health care culture of excess. Initially, it felt good to order a CT scan on everyone who had a fall or cardiac enzymes on anybody who had atypical chest pain. I felt...
Related topics: Medicare

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Organic Packaging To Protect Enzymes

As soon as you take medication, your body is already working on removing it from your body. According to UT Ph.D. student Robin Klem, encapsulins—a kind of hollow protein ball—have the potential to protect enzymes and other proteins that are...
Related topics: Proteins

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How Tiny Enzymes Reign Supreme In Worldwide Carbon Recycling

That white rot fungi on fallen logs in a forest, it's super important.

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Researchers Map The Formation Of Ducts Connecting Digestive Organs In Zebrafish

A specialised system of ducts transports bile and enzymes from the liver and pancreas to the intestine. In a new study, researchers from the University of Copenhagen have shown how this ductal system is formed. The new knowledge can help...
Related topics: Medical Research

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Formation Of Ducts Connecting Digestive Organs In Zebrafish

A specialized system of ducts transports bile and enzymes from the liver and pancreas to the intestine. Researchers have shown how this ductal system is formed. The new knowledge can help understanding how congenital diseases in that part of the...
Related topics: Medical Research

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Enzyme Toolkit Makes Biotechnology Globally Accessible

In 2016, Lenshina Agbor was working on her master's thesis in Cameroon, analyzing the DNA of a parasite that causes malaria in pregnant women. She imported the enzymes needed for her research from Europe, but struggled with the cost of purchasing...
Related topics: Biotechnology, DNA, Genetics, Parasites, Malaria, Medical Research

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The Cause Of Chewy Chicken Meat

University of Delaware researchers have discovered that lipoprotein lipase, an enzyme crucial for fat metabolism, may be contributing to wooden breast syndrome in broiler chickens.
Related topics: Medical Research

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Hormone Clue To Snail Shells' Spiral

An enzyme that makes the male sex hormones has unravelled a fresh clue about how snail shells come to be curly. 
Related topics: Hormones

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New Aci Guidance Provides Pathways For Stewardship Of Enzyme-containing Consumer Products

Enzymes bring significant benefits to laundry and cleaning products, including improved cleaning efficiencies. An updated publication from the American Cleaning Institute (ACI) provides a framework for consumer product manufacturers to develop...

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Genetics May Determine Who Benefits From Broccoli's Effects On Kidney Health

Deletion of the gene that codes for an enzyme called GSTM1 increased kidney injury in mice with hypertension and kidney disease, but supplementing the diet with broccoli powder lessened kidney injury in the genetically altered mice. In humans, high...
Related topics: Genetics, Kidney Disease, Hypertension, Diet

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Architecture Of A Bacterial Power Plant Decrypted

Both humans and many other creatures need oxygen for survival. In the conversion of nutrients into energy, oxygen is converted to water, for which the enzyme oxidase is responsible. It represents the last step of the so-called respiratory chain.
Related topics: Bacteria

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Researchers Halt Spread Of Breast Cancer By Blocking Metastasis-promoting Enzyme

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to...
Related topics: Medical Research, Breast Cancer, Cancer, Oncology, Metastasis

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