Glioblastoma

New Potential Target In Glioblastoma

Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a new study.
Related topics: Medical Research, Brain Tumors, Cancer, Oncology

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Five-year Overall Survival For Glioblastoma Persistently Low

THURSDAY, June 27, 2019 -- The percentage of patients achieving five-year survival following a glioblastoma diagnosis remains both steady and low, according to a study published online June 19 in Mayo Clinic Proceedings. J. Nathan Cantrell, from...
Related topics: Medical Research, Mayo Clinic

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Estudo: Tratamentos Mais Agressivos Sao Necessarios Para Melhorar A Taxa De Sobrevida De 5 Anos...

Apesar das melhorias nas taxas de sobrevida de curto e medio prazos para pacientes com glioblastoma, o tumor cerebral mais comum em adultos, a percentagem de pacientes que atinge a sobrevida de cinco anos continua baixa, de acordo com a nova...
Related topics: Cancer

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News Digest – Brain Tumour Awards, Car T Cell Therapy, Nhs ‘fast-tracking’ Drugs And Nice...

Boosting brain tumour research A year on from the death of Baroness Tessa Jowell, the former Labour cabinet minister diagnosed with glioblastoma who campaigned for funding and support for brain tumours, 3 newly-funded brain tumour research teams...
Related topics: Medical Research

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Approach Could Help In Treating Glioblastoma, Other Rare Cancers

Using a new approach that combines data from human tumors grown in mice with data from The Cancer Genome Atlas, a team led by University of Michigan Rogel Cancer Center researchers has uncovered several previously unknown biomarkers for...
Related topics: Cancer, Oncology, Genetics, Medical Research

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Macrophages' Pathway To Nurture Pten-deficient Glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers report.
Related topics: Genetics, Brain Tumors, Cancer, Medical Research

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Cancer-fighting Combination Targets Glioblastoma

An international team of researchers combined a calorie-restricted diet high in fat and low in carbohydrates with a tumor-inhibiting antibiotic and found the combination destroys cancer stem cells and mesenchymal cells, the two major cells found in...
Related topics: Cancer, Oncology, Medical Research, Calories, Diet, Antibiotics, Stem Cells

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Researchers Discover The Achilles' Heel Of An Aggressive Brain Cancer

Researchers have discovered a chink in the armor of the tumor cells of glioblastoma, a lethal brain cancer. Alongside the finding, the researchers also came up with a method for attacking this vulnerability. The results gained in experiments...
Related topics: Medical Research, Brain Tumors, Cancer, Oncology

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The Mechanism Of Action Of An Antitumor Drug Used For The Treatment Of Glioblastoma

The antibody mAb806 is used to treat glioblastoma, although its mechanism of action has been unknown until now. The study paves the way to extend treatment with mAb806 to more types of tumors and to the development of more personalised therapies.
Related topics: Medical Research, Cancer

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New Glioblastoma Vaccine Shows Promising Results In Phase Ib Clinical Trial

A brain-cancer vaccine more than 20 years in the making suspends cancer growth in patients enrolled in early-stage trial.
Related topics: Vaccines, Clinical Trials, Brain Tumors, Cancer, Oncology

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A New Way To Stop Chemotherapy-resistant Glioblastoma

Glioblastoma (GBM) is among the most common and malignant types of primary brain tumors in adults, and one with a poor prognosis. The tendency of this type of tumor to aggressively and widely spread through the brain makes it nearly impossible to...
Related topics: Chemotherapy, Cancer, Brain Tumors

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Pembrolizumab Before And After Resection Boosts Glioblastoma Outcomes (cme/ce)

(MedPage Today) -- "Timing matters" for anti-PD-1 immunotherapy, study suggests
Related topics: Medical Research

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Neoadjuvant Pd-1 Blockade Seems Effective In Glioblastoma

WEDNESDAY, Feb. 13, 2019 -- Neoadjuvant administration of programmed cell death protein 1 (PD-1) blockade seems to enhance local and systemic antitumor immune response in glioblastoma, according to a study published online Feb. 11 in Nature...
Related topics: Proteins, Medical Research

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For Recurrent Glioblastoma, Immunotherapy Before Surgery Appears To Help More Than Afterward

A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than using the drug afterward. In recent years, immunotherapy drugs, which harness the body’s immune system...
Related topics: Medical Research

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The Growing Role Of End-of-life Activists

Brittany Maynard was diagnosed with grade 2 astrocytoma, a form of brain cancer on January 1, 2014, her cancer also returned in April 2014, where her diagnosis was elevated to grade 4 astrocytoma, also known as glioblastoma, with a prognosis of...
Related topics: Activism, Brain Tumors, Cancer, Oncology

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The Hitchhiker's Guide To Defeating Glioblastoma

A team of investigators has begun looking at microRNAs in an entirely new way. Their approach has shown promising results in preclinical models, increasing survival in a murine model of glioblastoma by five-fold when combined with chemotherapy.
Related topics: Chemotherapy, Cancer

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A Bizarre Claim Of Right To Try

By ARTHUR CAPLAN, KELLY MCBRIDE FOLKERS, and ANDREW MCFAYDEN  A patient with glioblastoma recently received an experimental cancer vaccine at the University of California, Irvine. Notably, this is being hailed as the first case of someone utilizing...
Related topics: Cancer, Oncology, Vaccines, Medical Research

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Positivity: North Carolina Boy Battling Cancer Reunited With Dog After Man Makes 2,300-mile Trip To...

From North Carolina and Utah (HT Weasel Zippers): January 15, 2019 An 8-year-old North Carolina boy who received a devastating and unexpected diagnosis of glioblastoma while visiting family in Utah over the holidays has now been reunited with his...
Related topics: Cancer, Oncology

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This Bride's Dance With Her Terminally Ill Father Is Giving Us All The Feels

The bride's father had been diagnosed with glioblastoma and placed in hospice care shortly before her wedding.        

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Sex Differences Id'd In Response To Glioblastoma Treatment

FRIDAY, Jan. 4, 2019 -- Sex differences have been identified in response to therapy among glioblastoma (GBM) patients, according to a study published in the Jan. 2 issue of Science Translational Medicine. Wei Yang, Ph.D., from the Washington...
Related topics: Medical Research

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