Glioblastoma

Existing Drug Could Treat Aggressive Brain Cancer

A research team has found that a compound molecule used for drug delivery of insulin could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer.
Related topics: Brain Tumors, Cancer, Oncology, Medical Research, Insulin

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Medical News Today: New Immunotherapy Shows Promise Against Brain Tumors In Mice

Scientists have demonstrated a new immunotherapy that can deliver checkpoint inhibitors across the blood-brain barrier to fight glioblastoma in mice.
Related topics: Brain Tumors, Cancer

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Can The Circadian Clock In Cancer Cells Help Defeat A Deadly Brain Cancer?

Scientists at USC and UC San Diego have discovered a potential novel target for treating glioblastoma, the deadly brain cancer that took the life of ... Read more
Related topics: Brain Tumors, Cancer, Oncology, Medical Research

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Aggressive Brain Tumor Could Be Diagnosed With Simple Blood Test In Future

New research by Sussex scientists could be the first step towards developing a blood test to diagnose the most aggressive type of brain tumour, known as Glioblastoma. A team from Professor Georgios Giamas’ lab at the University of Sussex has...
Related topics: Brain Tumors, Cancer, Blood Test, Medical Research

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Interregional Differences In Somatic Genetic Landscape Diversify Prognosis In Glioblastoma

Researchers have conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma (GBM), proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an original Japanese...
Related topics: Genetics, Medical Research

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Boston Researchers Try Drug-controlled Gene Therapy On Deadly Brain Tumor

The study on glioblastoma is the first example of such on-and-off gene therapy in humans, researchers say.
Related topics: Medical Research, Genetics, Brain Tumors, Cancer

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Adding Ms Drug To Targeted Cancer Therapy May Improve Glioblastoma Outcomes

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor's root, according to a new study.
Related topics: Cancer, Oncology, Multiple Sclerosis, Stem Cells, Medical Research

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New Potential Target In Glioblastoma

Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a new study.
Related topics: Medical Research, Brain Tumors, Cancer, Oncology

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Five-year Overall Survival For Glioblastoma Persistently Low

THURSDAY, June 27, 2019 -- The percentage of patients achieving five-year survival following a glioblastoma diagnosis remains both steady and low, according to a study published online June 19 in Mayo Clinic Proceedings. J. Nathan Cantrell, from...
Related topics: Medical Research, Mayo Clinic

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Estudo: Tratamentos Mais Agressivos Sao Necessarios Para Melhorar A Taxa De Sobrevida De 5 Anos...

Apesar das melhorias nas taxas de sobrevida de curto e medio prazos para pacientes com glioblastoma, o tumor cerebral mais comum em adultos, a percentagem de pacientes que atinge a sobrevida de cinco anos continua baixa, de acordo com a nova...
Related topics: Cancer

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News Digest – Brain Tumour Awards, Car T Cell Therapy, Nhs ‘fast-tracking’ Drugs And Nice...

Boosting brain tumour research A year on from the death of Baroness Tessa Jowell, the former Labour cabinet minister diagnosed with glioblastoma who campaigned for funding and support for brain tumours, 3 newly-funded brain tumour research teams...
Related topics: Medical Research

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Better Treatments Needed To Boost Brain Cancer Survival: Study

FRIDAY, June 21, 2019 -- Glioblastoma brain cancer remains one of deadliest tumors, and new research shows five-year survival rates remain low for patients with the disease. While there have been improvements in short- and medium-term survival...
Related topics: Brain Tumors, Cancer, Oncology, Medical Research

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Approach Could Help In Treating Glioblastoma, Other Rare Cancers

Using a new approach that combines data from human tumors grown in mice with data from The Cancer Genome Atlas, a team led by University of Michigan Rogel Cancer Center researchers has uncovered several previously unknown biomarkers for...
Related topics: Cancer, Oncology, Genetics, Medical Research

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Macrophages' Pathway To Nurture Pten-deficient Glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers report.
Related topics: Genetics, Brain Tumors, Cancer, Medical Research

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Cancer-fighting Combination Targets Glioblastoma

An international team of researchers combined a calorie-restricted diet high in fat and low in carbohydrates with a tumor-inhibiting antibiotic and found the combination destroys cancer stem cells and mesenchymal cells, the two major cells found in...
Related topics: Cancer, Oncology, Medical Research, Calories, Diet, Antibiotics, Stem Cells

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The Mechanism Of Action Of An Antitumor Drug Used For The Treatment Of Glioblastoma

The antibody mAb806 is used to treat glioblastoma, although its mechanism of action has been unknown until now. The study paves the way to extend treatment with mAb806 to more types of tumors and to the development of more personalised therapies.
Related topics: Medical Research, Cancer

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Scientists 'reverse Engineer' Brain Cancer Cells To Find New Targets For Treatment

Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death in children and young adults. Scientists have 'reverse engineered' brain cancer stem cells gene by...
Related topics: Brain Tumors, Cancer, Oncology, Stem Cells, Genetics

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New Glioblastoma Vaccine Shows Promising Results In Phase Ib Clinical Trial

A brain-cancer vaccine more than 20 years in the making suspends cancer growth in patients enrolled in early-stage trial.
Related topics: Vaccines, Clinical Trials, Brain Tumors, Cancer, Oncology

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A New Way To Stop Chemotherapy-resistant Glioblastoma

Glioblastoma (GBM) is among the most common and malignant types of primary brain tumors in adults, and one with a poor prognosis. The tendency of this type of tumor to aggressively and widely spread through the brain makes it nearly impossible to...
Related topics: Chemotherapy, Cancer, Brain Tumors

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Pembrolizumab Before And After Resection Boosts Glioblastoma Outcomes (cme/ce)

(MedPage Today) -- "Timing matters" for anti-PD-1 immunotherapy, study suggests
Related topics: Medical Research

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