Hepatocellular Carcinoma

Genes Linked With The Most Common Liver Cancer

Researchers have provided the first summary of the experimental evidence supporting the AKR1B10 enzyme as a promising therapeutic target for Hepatocellular carcinoma (HCC), based on a review of more than 50 studies published since this gene was...
Related topics: Genetics, Liver Cancer, Cancer, Oncology, Medical Research, Enzymes

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Direct-acting Antivirals Cut Mortality In Chronic Hepatitis C

TUESDAY, Feb. 12, 2019 -- For adults with chronic hepatitis C virus (HCV) infection, direct-acting antivirals are associated with a reduced risk for mortality and hepatocellular carcinoma, according to a study published online Feb. 11 in The...
Related topics: Hepatitis, Hepatitis C, Virus, Virology, Medical Research

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Liver Transplant Survival May Improve With Race Matching

WEDNESDAY, Jan. 16, 2019 -- For African-American patients with hepatocellular carcinoma (HCC) undergoing liver transplantation, donor-recipient race matching is associated with improved survival, according to a study published online Jan. 10 in...
Related topics: African-American, Medical Research

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Low Pni Predicts Poor Liver Cancer Outcomes

(MedPage Today) -- Meta-analysis supports prognostic tool for hepatocellular carcinoma
Related topics: Liver Cancer, Cancer, Oncology

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Roche's Tecentriq Gets Breakthrough Therapy Status For Hcc

Roche Holding AG RHHBY announced that the FDA has granted breakthrough therapy designation to its immuno-oncology drug, Tecentriq, in combination with Avastin for the first-line treatment of advanced hepatocellular carcinoma (HCC).The...
Related topics: Food And Drug Administration, Cancer, Oncology, Avastin

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Cabozantinib Improves Survival In Advanced Hepatocellular Cancer

FRIDAY, July 6, 2018 -- Cabozantinib results in significantly longer overall and progression-free survival than placebo among patients with advanced hepatocellular carcinoma, according to a study published in the July 5 issue of the New England...
Related topics: Cancer, Oncology, Placebo, Medical Research

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Reduced Overall Survival For Alcohol-related Liver Cancer

WEDNESDAY, March 28, 2018 -- Reduced overall survival (OS) is seen for patients with alcohol-related hepatocellular carcinoma (HCC), according to a study published online March 28 in Cancer. Charlotte E. Costentin, M.D., from the Public Hospital...
Related topics: Alcohol, Liver Cancer, Cancer, Oncology, Medical Research

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Exelixis Slides Despite Positive Late-stage Results

Shares of Exelixis slipped on Wednesday after the company reported results from its late-stage trial of cabozantinib for advanced hepatocellular carcinoma.

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Spermidine-rich Foods May Prevent Liver Cancer, Extend Lifespan

Spermidine--a compound found in foods like aged cheese, mushrooms, soy products, legumes, corn and whole grains--seems to prevent (at least in animal models) liver fibrosis and hepatocellular carcinoma, which is the most common type of liver cancer.
Related topics: Liver Cancer, Cancer, Oncology

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Nccn Awards 3 Grants To Investigators To Study Bavituximab In Combination With Other Therapeutic...

The NCCN Oncology Research Program has awarded research grants to three investigators to study bavituximab in glioblastoma, head and neck cancer, and hepatocellular carcinoma.
Related topics: Medical Research, Cancer, Oncology, Glioblastoma

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Targeted Treatment For Liver Cancer Under Way

A new molecular mechanism has been discovered that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer, report scientists.
Related topics: Liver Cancer, Cancer, Oncology, Medical Research

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New Hepatocellular Carcinoma Prognostic Model Improves Prediction Of Patient Survival

The ITA.LI.CA prognostic system, a model integrating tumor staging, liver function, functional status, and alpha-fetoprotein level, builds on previous models of hepatocellular carcinoma (HCC) prognosis and shows superior survival prediction in...
Related topics: Cancer, Liver Cancer

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Antiviral Therapy Prolongs Survival In Immune Tolerant Hepatitis B Patients

A new study demonstrates that the use of antiviral therapy for patients in the immune tolerant phase of hepatitis B (HBV) prolongs overall survival and reduces the risk of the most common form of liver cancer (Hepatocellular Carcinoma, HCC) and...
Related topics: Hepatitis, Hepatitis B, Medical Research, Liver Cancer, Cancer, Oncology

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Screening For Hepatocellular Carcinoma

Learn the risk factors for hepatocellular carcinoma, and who to screen, how often to screen, and what tools should be used. Medscape Gastroenterology

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Efficacy And Safety Of Oral Branched-chain Amino Acid Supplementation In Patients Undergoing...

Most hepatocellular carcinoma (HCC) patients have complications, including cirrhosis and malnutrition. The efficacy of dietary supplementation with oral branched-chain amino acids (BCAAs) in HCC patients undergoing interventions has not been...
Related topics: Cirrhosis

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Airborne Hydrocarbons: Liver Cancer Cause?

(MedPage Today) -- Organic air pollutants tied to hepatocellular carcinoma incidence in Texas.
Related topics: Liver Cancer, Cancer, Oncology

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Tekmira Clears Regulatory Hurdles For Liver Cancer Trial

Share of Tekmira Pharmaceuticals (TKMR +12.8%) are up in below-average volume in response to its report that all the regulatory requirements have been met to begin a Phase 1/2 clinical trial for TKM-PLK1 as a treatment for hepatocellular carcinoma....
Related topics: Liver Cancer, Cancer, Oncology, Clinical Trials

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Bayer/amgen's Nexavar Fails In Late-stage Study - Analyst Blog

The HealthCare segment at Bayer (BAYRY) and partner, Amgen Inc. (AMGN), announced disappointing results from a phase III STORM (Sorafenib as Adjuvant Treatment in the Prevention of Recurrence of Hepatocellular Carcinoma) study on Nexavar. The...
Related topics: Amgen

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Fda Approves New Phase Iii Trial For Celesion's Thermodox

The FDA has cleared Celesion's (CLSN +6.35%) Optima Phase III trial of its ThermoDox therapy for treating hepatocellular carcinoma (HCC), the most common type of liver cancer. In a previous late-stage study, called Heat, ThermoDox failed...
Related topics: Food And Drug Administration, Liver Cancer, Cancer, Oncology

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Diabetes Identified As Risk Factor For Liver Cancer Across Ethnic Groups

Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, according to...
Related topics: Diabetes, Liver Cancer, Cancer, African-American, Oncology

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