Kidney Cancer

Can More Children's Kidneys Be Spared?

For most children with renal masses, the standard of care has long been to remove the entire affected kidney--which is the protocol for Wilms tumor, the most common kidney cancer in children. But is it possible for surgeons to perform partial...
Related topics: Cancer, Oncology

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Merck's (mrk) Keytruda Gets Europe Nod For Two Carcinomas

Merck MRK announced that the European Commission approved its blockbuster anti-PD-1 drug, Keytruda, in combination with Eisai’s cancer drug Lenvima, for treating first-line kidney cancer and recurrent endometrial carcinoma.The Keytruda...
Related topics: Merck & Co, Cancer, Endometrial Cancer, Oncology

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Ut Southwestern Launches Spore-funded National Resource To Advance Precision Medicine For Kidney...

Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse...
Related topics: Cancer, Oncology, Medical Research

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Belzutifan Induced Strong Responses In Patients With Von Hippel-lindau Disease-associated Kidney...

Results from a Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center showed that treatment with belzutifan, a small-molecule inhibitor of hypoxia-inducible factor (HIF)-2a, achieved strong clinical activity in...
Related topics: Kidney Disease, Cancer, Oncology, Clinical Trials, Medical Research

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Fda Oks Pd-1 Inhibitor For Adjuvant Treatment Of Kidney Cancer

(MedPage Today) -- The FDA approved pembrolizumab (Keytruda) for the adjuvant treatment of renal cell carcinoma (RCC) for patients who have an intermediate-high or high risk of recurrence following nephrectomy, or following nephrectomy and...
Related topics: Food And Drug Administration, Cancer, Oncology

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Serial Radiation Therapy Is Safe And Effective As Alternative Treatment To Systemic Therapy For...

In a new single-arm study, researchers reported that radiation therapy as monotherapy is a safe and effective noninvasive treatment for oligometastatic renal cell carcinoma (RCC).
Related topics: Cancer, Oncology, Medical Research

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Targeted Drug Shows Activity Against Brain Metastases In Kidney Cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant...
Related topics: Brain Tumors, Cancer, Oncology

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Unusual Kidney Cancer Feature Sheds Light Into How Cancers Invade And Metastasize

How cancers metastasize remains poorly understood. The process begins when cancer cells break off from a tumor and invade blood and lymphatic vessels, the body's alleyways. But studying invasion - typically a microscopic process - is challenging.
Related topics: Cancer, Oncology

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Pharma Pushback On Pricing; Fatal Screening Exclusion; Good News For Kidney Cancer

(MedPage Today) -- In an open letter to Congress, pharmaceutical companies said that allowing Medicare to negotiate drug prices "would threaten patients' access to medicines and sacrifice future medical advances," lobbying group PhRMA announced...
Related topics: Cancer, Oncology, Medicare

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Removing Race Term From Ckd-epi Could Worsen Cancer Care For Blacks

WEDNESDAY, Sept. 1, 2021 -- Removing race from the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation will calculate a lower estimated glomerular filtration rate (eGFR) for Black patients and exclude more from receiving...
Related topics: Cancer, Oncology, Kidney Disease

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Fda Oks Pembro Plus Lenvatinib For First-line In Kidney Cancer

Results from the phase 3 CLEAR trial showed significant survival benefits with the combination when compared with lenvatinib-everolimus or sunitinib monotherapy. FDA Approvals
Related topics: Food And Drug Administration, Cancer, Oncology

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Most Comprehensive Review Yet Of Keto Diets Finds Heart Risks, Cancer Risk, Dangers To Pregnant...

In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.
Related topics: Cardiovascular Disease, Cancer, Oncology, Kidney Disease

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Urine Test Differentiates Kidney Cancer From Benign Lesions

For patients with kidney lesions, urine tests under development can differentiate renal cell cancer from benign masses, say investigators. Medscape Medical News
Related topics: Cancer, Oncology

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Ut Southwestern Investigators Report First Analysis Of Pioneering Kidney Cancer Radiation Approach...

A new approach using precisely targeted, high-dose radiation to treat invasive kidney cancer proves safe, based on a clinical trial by the UT Southwestern Harold C. Simmons Comprehensive Cancer Center's kidney cancer program. The study, published in...
Related topics: Cancer, Oncology, Clinical Trials, Medical Research

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New Microscopy Method Reveals Single Childhood Cancer Cells In Unprecedented Detail

A new technique to look at tumors under the microscope has revealed the cellular make-up of Wilm's tumors, a childhood kidney cancer, in unprecedented detail. This new approach could help understand how tumors develop and grow, and fuel research...
Related topics: Cancer, Oncology, Microscopes, Medical Research

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Cellular Signatures Of Kidney Tumors Discovered

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers. The findings confirm that these cancers have their origin in specific forms of developmental cells present in the maturing fetus.
Related topics: Cancer, Medical Research, Oncology

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'happy Death Day' Director Christopher Landon Diagnosed With Kidney Cancer, Urges Fans To Watch...

Christopher Landon, the director of the Happy Death Day movies, is opening up about being diagnosed with kidney cancer. The 46-year-old filmmaker says he was rushed into emergency surgery about a week ago to have part of his kidney removed. Chris...
Related topics: Cancer, Oncology

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New Insights On Sarcomatoid Kidney Cancer: Roswell Park Reports Clear Benefit From Checkpoint...

New collaborative research shows that treatment with immune checkpoint inhibitors (ICIs) has led to a significant improvement in survival and response rates among patients with a particularly aggressive type of kidney cancer: advanced sarcomatoid...
Related topics: Cancer, Oncology, Medical Research

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Analysis Reveals How Kidney Cancer Develops And Responds To Treatment

By sequencing the RNA of individual cells within multiple benign and cancerous kidney tumors, researchers from the University of Michigan Rogel Cancer Center have identified the cells from which different subtypes originate, the pathways involved...
Related topics: Cancer, Oncology, Genetics, Medical Research

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Immunotherapy Drug Delays Recurrence In Kidney Cancer Patients

Treatment with an immunotherapy drug following kidney cancer surgery, prolonged disease-free survival rates in patients at high risk for recurrence, according to an interim report of a phase 3 clinical trial of adjuvant immunotherapy in this patient...
Related topics: Kidney Disease, Cancer, Oncology, Clinical Trials

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