Lung Cancer

Onconova (ontx) Kras Inhibitor Shows Activity In Lung Cancer

Onconova Therapeutics, Inc. ONTX announced promising preliminary data from the phase I/II study evaluating its oral pipeline candidate, rigosertib, in combination with Bristol-Myers’ BMY immune checkpoint inhibitor, Opdivo (nivolumab), in...
Related topics: Cancer, Oral Cancer, Oncology, Medical Research

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Top Science From The World Conference On Lung Cancer

(MedPage Today) -- Hello, and thanks for joining us for the latest in-between-isode of Anamnesis from MedPage Today. IASLC [International Association for the Study of Lung Cancer] 2021 was a virtual event this year due to COVID-19, but MedPage...
Related topics: Cancer, Oncology, Medical Research

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Immunotherapy-chemo Offers Survival Advantage In Low Pd-l1 Nsclc

(MedPage Today) -- Adding durvalumab (Imfinzi) and tremelimumab to chemotherapy improved progression-free and overall survival in patients with metastatic, nonsquamous non-small cell lung cancer (NSCLC), according to the phase III POSEIDON trial...
Related topics: Chemotherapy, Cancer, Oncology

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Study: Global Cancer Risk From Burning Organic Matter Comes From Unregulated Chemicals

Whenever organic matter is burned, such as in a wildfire, a power plant, a car’s exhaust, or in daily cooking, the combustion releases polycyclic aromatic hydrocarbons (PAHs) — a class of pollutants that is known to cause lung cancer. There are...
Related topics: Medical Research, Cancer, Oncology

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Right Program Could Turn Immune Cells Into Cancer Killers

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different 'program' that makes them less effective than immune cells in patients whose cancers respond to these immune...
Related topics: Cancer, Oncology

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Roche (rhhby) Lung Cancer Drug Gets Positive Chmp Opinion

Roche RHHBY has announced that the European Medicines Agency’s (“EMA”) Committee for Medicinal Products for Human Use (CHMP) has given a positive opinion for Gavreto (pralsetinib).Gavreto is a once-daily, oral targeted treatment...
Related topics: Cancer, Oral Cancer, Oncology

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Another Possible Option For Her2-mutated Non-small Cell Lung Cancer

(MedPage Today) -- More than half of patients with treatment-refractory HER2-positive non-small cell lung cancer (NSCLC) responded to an anti-HER2 antibody-drug conjugate, data from a preliminary trial showed. Fifty of 91 patients responded to...
Related topics: Cancer, Oncology

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Antibody-drug Conjugate Shows Impressive Activity In Patients With Non-small Cell Lung Cancer With...

More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent to a highly targeted...
Related topics: Cancer, Oncology, Genetics, Chemotherapy

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Fda Ok's New Drug For Lung Cancers With Exon 20 Mutations

(MedPage Today) -- The FDA approved mobocertinib (Exkivity) as a second-line treatment for locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations, Takeda Pharmaceuticals announced on Wednesday...
Related topics: Food And Drug Administration, Cancer, Oncology, Genetics

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How A Plant Virus Could Protect And Save Your Lungs From Metastatic Cancer

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs. The treatment not only slowed tumor growth in the lungs of...
Related topics: Virus, Virology, Cancer, Oncology, Medical Research

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Long-term Benefit Of Sabr For Operable Early-stage Nsclc Shown In New Study

A new study showed that stereotactic ablative radiotherapy (SABR) was as effective as surgery at providing long-term benefits to patients with operable early-stage non-small cell lung cancer (NSCLC) and generated minimal side effects. The study is...
Related topics: Medical Research, Cancer, Oncology

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Cancer Vaccine May Boost Anti-egfr Efficacy In Non-small Cell Lung Cancer

(MedPage Today) -- Adding a vaccine against epidermal growth factor (EGF) to an EGFR inhibitor led to a high response rate and durable activity in advanced EGFR-mutated non-small cell lung cancer (NSCLC), a small pilot study showed. The treatment...
Related topics: Cancer, Oncology, Vaccines, Medical Research

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How A Plant Virus Could Protect And Save Your Lungs From Metastatic Cancer

Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.
Related topics: Virus, Virology, Cancer, Oncology, Medical Research

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Oncologists Still Failing 'woefully' At Molecular Testing

Oncologist Jack West explores why molecular testing in advanced lung cancer is not happening often enough in the clinic Medscape Oncology
Related topics: Cancer, Oncology

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Novel Adc Promising In Certain Non-squamous Lung Cancers

(MedPage Today) -- A novel antibody-drug conjugate (ADC) yielded responses in about a fourth of patients with heavily pretreated, MET-positive non-small cell lung cancer (NSCLC), a multicenter phase II trial showed. The highest objective response...
Related topics: Cancer, Oncology

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Long-term Benefit Of Sabr For Operable Early-stage Nsclc Shown In New Study

A new study from researchers at The University of Texas MD Anderson Cancer Center showed that stereotactic ablative radiotherapy (SABR) was as effective as surgery at providing long-term benefits to patients with operable early-stage non-small cell...
Related topics: Medical Research, Cancer, Oncology

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White Blood Cells That Can Help Destroy Malignant Tumors

A new study at Tel Aviv University found that eosinophils - a type of white blood cells - are recruited to the battle against cancer metastases in the lungs.
Related topics: Cancer, Medical Research, Oncology

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Meta-analysis Confirms Benefits Of Low-dose Ct Screening For Lung Cancer

(MedPage Today) -- Low-dose computed tomography (LDCT) for lung cancer screening was associated with a reduction in lung cancer mortality, according to a meta-analysis of nine international randomized controlled trials. When the latest U.K. Lung...
Related topics: Cancer, Oncology

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Immuno-oncology Combo Active In Recurrent Egfr/alk Positive Nsclc

(MedPage Today) -- Patients with recurrent EGFR/ALK-positive non-small cell lung cancer (NSCLC) obtained durable remissions with the combination of pembrolizumab (Keytruda) and chemotherapy, a small prospective study showed. The immuno-oncology...
Related topics: Cancer, Oncology, Chemotherapy, Medical Research

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Nhs Lung Cancer Patients In England To Get Early Access To ‘breakthrough’ Cancer Drug

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a first-of-its-kind cancer drug – capable of targeting a gene mutation that causes some of the most aggressive cancers – to treat a certain form of lung cancer. The...
Related topics: Cancer, Oncology, Genetics

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