Lymphoma

Engineering Car T Cells To Eliminate Problems

]]>(MedPage Today) -- A novel anti-CD19 CAR T-cell therapy attained a high response rate with minimal neurotoxicity in patients with advanced B-cell lymphoma, according to a preliminary clinical trial. The results showed that 11 of 20 patients...
Related topics: Clinical Trials

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This Study Just Found A New Way To Kill Cancer (maybe For Good)

Ingo Ringshausen Technology, This new treatment method might benefit hundreds of thousands of people currently diagnosed who are under observation or treatment. Cancer of the immune system, called lymphoma or leukaemia, generally affects the...
Related topics: Medical Research, Cancer, Oncology, Leukemia

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Future Of T-cell Lymphoma Treatment

]]>(MedPage Today) -- Peripheral T-cell lymphoma accounts for about 7% of all non-Hodgkin lymphoma cases. Over the last decade, new drugs have emerged for this condition, with new findings on some of these presented at the recent 2019 American...

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Fianceé Of Late Espn Reporter Edward Aschoff Reveals He Passed From Non-hodgkin’s Lymphoma

Source: Mr.Lomein/ Getty Images / Getty Edward Aschoff’s Fianceé Reveals He Had Stage 4 non-Hodgkin’s Lymphoma In His Lungs The fianceé of ESPN college football reporter Edward Aschoff, who passed away on December 24 (which was also...
Related topics: Espn

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Markazi: A Time When The Past And Present Painfully Collided

The death of his friend Edward Aschoff from undetected non-Hodgkin's lymphoma brings back painful memories for Times columnist Arash Markazi.

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Mosunetuzumab For Aggressive Lymphoma: 'not A Home Run'

Dr Ann LaCasce gives her take on whether the investigational agent mosunetuzumab fills an 'unmet need' for aggressive lymphoma. Medscape Oncology
Related topics: Cancer, Oncology

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Clinical Challenge: Treating Relapsed Follicular Lymphoma

]]>(MedPage Today) -- The currently available treatments for follicular lymphoma are not curative, meaning that most patients will experience disease relapse and progression. Some patients with follicular lymphoma may experience long-term...

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Survival Up For Chronic Lymphocytic Leukemia 1995 To 2017

THURSDAY, Dec. 26, 2019 -- For patients with chronic lymphocytic leukemia (CLL) in routine care, overall survival improved from 1995 to 2017, according to a study recently published in Leukemia & Lymphoma. Rudolf Weide, M.D., from the Praxis...
Related topics: Leukemia, Medical Research

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Trump's Epa Goes To Bat For Bayer As Company Fights $25 Million Verdict In Roundup Cancer Case

Andrea Germanos, staff writerThe chemical company is asking a federal appeals court to reverse its ruling in favor of a California man suffering from non-Hodgkin's lymphoma.
Related topics: Cancer, Oncology

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Clinical Challenge: Maintenance Tx For Advanced Follicular Lymphoma

]]>(MedPage Today) -- Many factors go into the decision about whether or not a patient with advanced follicular lymphoma should be given maintenance therapy after completing the induction regimen. Among these factors are the patient's depth of...

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Novel Cell-based Therapy Induces Cell Death In Sensitive And Resistant Non-hodgkin Lymphoma Models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are...
Related topics: Cancer, Oncology

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Study: Most With Early Dlbcl Can Skip Rt

]]>(MedPage Today) -- ORLANDO -- Almost 90% of patients with limited-stage diffuse large B-cell lymphoma (DLBCL) remained alive without disease progression at 5 years with a treatment strategy that omitted radiation therapy in most cases,...
Related topics: Medical Research

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Ash: Allohsct Feasible After Pd-1, Pd-l1 Mab In Hodgkin Lymphoma

TUESDAY, Dec. 10, 2019 -- Allogeneic hematopoietic stem cell transplantation (alloHSCT) performed after programmed cell death 1 (PD-1) or programmed cell death ligand 1 (PD-L1) monoclonal antibody (mAB) treatment seems feasible for patients with...
Related topics: Stem Cells

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Treatment With Pd-1 Inhibitor Prior To Stem Cell Transplant Is Safe, Effective For Patients With...

A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma.
Related topics: Stem Cells, Medical Research

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Ash: Pet Helps Tailor Therapy In Limited-stage Dlbcl

MONDAY, Dec. 9, 2019 -- Positron emission tomography (PET)-directed therapy results in excellent outcomes for patients with stage I/II diffuse large B-cell lymphoma (DLBCL), according to a study presented at the annual meeting of the American...
Related topics: Positron Emission Tomography, Medical Research

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'off-the-shelf' Therapy Active After Car T-cell Failure

]]>(MedPage Today) -- ORLANDO -- Half of patients with relapsed, difficult-t0-treat non-Hodgkin lymphoma (NHL) responded to an investigational bispecific antibody, including patients resistant or refractory to CAR T-cell therapy, data from a...

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Year In Review: Lymphoma

]]>(MedPage Today) -- The top lymphoma news in 2019 included broadened Medicare coverage of chimeric antigen receptor (CAR) T-cell therapy, further developments with this novel treatment, a half-dozen notable approvals from the FDA, and escalated...
Related topics: Medicare, Food And Drug Administration

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Retrospective Analysis Identifies Need For Better Classification Of Rare Lymphoma

In what is believed to be one of the largest studies of a rare disorder known as primary cutaneous gamma delta T-cell lymphoma, Rutgers Cancer Institute investigators and other collaborators examined characteristics, treatment patterns and outcomes...
Related topics: Cancer, Oncology

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Risk For Hodgkin Lymphoma Increased With Allergic Disease, Eczema

TUESDAY, Dec. 3, 2019 -- The risk for Hodgkin lymphoma (HL) is increased in association with immunosuppression, allergic disease, and eczema, according to a study published online Nov. 12 in the Journal of Allergy and Clinical Immunology. Meena...
Related topics: Allergies, Medical Research

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Calcium Signaling Identified As Exploitable Target In Addressing Drug Resistance To Non-hodgkin...

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel...
Related topics: Genetics, Cancer, Oncology, Medical Research

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