Melanoma

The Health Benefits Of Coffee

Drinking coffee has been linked to a reduced risk of all kinds of ailments, including Parkinson’s disease, melanoma, prostate cancer, even suicide.
Related topics: Parkinson's, Skin Cancer, Cancer, Prostate Cancer, Oncology

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Barriers To Physician Skin Exam Id'd For Young Melanoma Survivors

WEDNESDAY, June 9, 2021 -- Barriers to health care access, especially cost, are associated with increased odds of not having an annual physician skin examination (PSE) among young melanoma survivors, according to a research letter published online...
Related topics: Skin Cancer, Cancer, Medical Research

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Adjuvant Anti-pd-1 Misses On Os In High-risk Melanoma

(MedPage Today) -- A year of adjuvant pembrolizumab (Keytruda) reduced the risk of relapse in high-risk melanoma compared with former standards of care, but failed to improve overall survival (OS), a phase III trial found. Relapse-free survival...
Related topics: Skin Cancer, Cancer

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Analyzing The Tumor Microenvironment At The Single Cell Level Sheds Light On Metastatic Melanoma...

In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers reveal how different therapies impact the surrounding immune environment of metastatic melanoma tumors according to location and identify a rare population of...
Related topics: Cancer, Skin Cancer, Medical Research, Oncology

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Dual Immunotherapy Regimen Delays Cancer Progression In Patients With Advanced Melanoma

A treatment regimen for patients with advanced melanoma that combines the immunotherapy agents relatlimab (anti-LAG-3) and nivolumab (anti-PD-1) delayed time to cancer progression significantly more than nivolumab alone, according to results of a...
Related topics: Cancer, Skin Cancer, Oncology, Medical Research

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Md Anderson Researchers Present New Findings In Targeted And Combination Therapies At 2021 Asco...

Several Phase II clinical trials conducted by researchers from The University of Texas MD Anderson Cancer Center show promising results for patients with melanoma, breast cancer, HER2-positive tumors and ovarian cancer. The results of these studies,...
Related topics: Medical Research, American Society Of Clinical Oncology, Clinical Trials, Breast Cancer, Cancer, Ovarian Cancer, Skin Cancer, Oncology

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Scientists Reveal Role Of Genetic Switch In Pigmentation And Melanoma

A study reveals new insights about a protein called CRTC3, a genetic switch that could potentially be targeted to develop new treatments for melanoma by keeping the switch turned off.
Related topics: Genetics, Skin Cancer, Cancer, Medical Research, Proteins

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Immunotherapy Combination Shows Benefit For Patients With Advanced Melanoma, Phase 3 Trial Shows

A combination of two drugs that target different proteins on immune system T cells kept advanced melanoma in check significantly longer than one of the drugs alone in a phase 3 clinical trial involving 714 patients. Dana-Farber Cancer Institute...
Related topics: Skin Cancer, Cancer, Clinical Trials, Proteins, Dana Farber Cancer Institute, Oncology

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Melanoma Can Strike Your Nails: Here's How To Check

SUNDAY, May 16, 2021 -- When checking your body for signs of skin cancer, don't overlook your nails. The American Academy of Dermatology (AAD) points out that skin cancer -- including melanoma, the deadliest type -- can develop under and around...
Related topics: Skin Cancer, Cancer, Oncology, Dermatology

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Cancer Has Ripple Effect On Distant Tissues

A new study with zebrafish shows that a deadly form of skin cancer -- melanoma -- alters the metabolism of healthy tissues elsewhere in the body. The research suggests that these other tissues could potentially be targeted to help treat cancer.
Related topics: Cancer, Skin Cancer, Oncology, Medical Research

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New Research Outlines A Critical Driver In An Immune Cell's Defense Against Melanoma

Researchers have found critical new insights into how cells defend against melanoma. The team describes how an enzyme called nicotinamide phosphoribosyltransferase, or NAMPT, initiates antitumor activity. The researchers suggest that new therapies...
Related topics: Medical Research, Skin Cancer, Cancer, Enzymes

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New Therapy Target For Malignant Melanomas In Dogs

Scientists have shown that the biological molecule PD-L1 is a potential target for the treatment of metastasized oral malignant melanoma in dogs.
Related topics: Skin Cancer, Cancer

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Chronic Adverse Effects From Anti-pd-1 Immunotherapies Common

FRIDAY, April 16, 2021 -- Chronic immune-related adverse effects after adjuvant treatment with anti-programmed cell death 1 (anti-PD-1) immunotherapies for melanoma are more common than previously thought, according to a study published online...
Related topics: Skin Cancer, Cancer, Medical Research

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Tebentafusp Improves Os: A First In Metastatic Uveal Melanoma

First-line tebentafusp significantly improved overall survival (OS) when compared with immunotherapy or chemotherapy in patients with metastatic uveal melanoma in a phase 3 trial. Medscape Medical News
Related topics: Skin Cancer, Cancer, Chemotherapy

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Tanning Bed Ban For Minors? Ai For Colon Cancer Dx; Blood Cancers And Covid Vax

(MedPage Today) -- A ban on tanning bed use by minors could prevent thousands of cases of melanoma and save millions of dollars in healthcare costs. (Cancer) Researchers have developed the first cervical cancer model derived from human tissue...
Related topics: Colon Cancer, Cancer, Cervical Cancer, Skin Cancer, Oncology, Medical Research

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Moffitt Investigators Identify Sting Gene Methylation That Allows Melanoma To Evade The Immune...

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.
Related topics: Genetics, Skin Cancer, Cancer, Oncology

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Novel Immunotherapy Approach To Fight Melanoma

Researchers have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response to help treat melanoma.
Related topics: Skin Cancer, Cancer, Medical Research

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Thiazides May Up Risk For Skin Cancer In Older Adults

MONDAY, April 12, 2021 -- Higher exposure to thiazides is associated with increased rates of incident keratinocyte carcinoma and melanoma among older adults, according to a study published online April 12 in CMAJ, the journal of the Canadian...
Related topics: Skin Cancer, Cancer, Oncology, Medical Research

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Nivolumab Alone Prevails In Resected Melanoma

(MedPage Today) -- Dual checkpoint blockade with nivolumab (Opdivo) plus ipilimumab (Yervoy) failed to improve outcomes as adjuvant therapy for resected melanoma over nivolumab alone, the CheckMate 915 trial found. In the intent-to-treat (ITT...
Related topics: Skin Cancer, Cancer

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Practice-changing Results In Metastatic Uveal Melanoma

(MedPage Today) -- A novel bispecific protein significantly improved overall survival (OS) in metastatic uveal melanoma as compared with investigator's choice of treatment, including checkpoint inhibitors, a randomized trial showed. Patients...
Related topics: Skin Cancer, Cancer, Proteins

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