Metastasis

Preventing Pancreatic Cancer Metastasis By Keeping Cells 'sheltered In Place'

Scientists have shown that pancreatic cancer metastasis -- when tumor cells gain the deadly ability to migrate to new parts of the body -- can be suppressed by inhibiting a protein called Slug that regulates cell movement. The study also revealed...
Related topics: Pancreatic Cancer, Cancer, Oncology, Proteins, Medical Research

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Shift In Treatment Modalities Associated With Improved Outcomes In Uveal Melanoma Patients With...

New retrospective study indicates that the shift of treatment from systemic chemotherapies to liver-directed therapies provides survival benefits.
Related topics: Skin Cancer, Melanoma, Cancer, Medical Research

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Shift In Treatment Modalities Associated With Improved Outcomes In Uveal Melanoma Patients With...

New retrospective study indicates that the shift of treatment from systemic chemotherapies to liver-directed therapies provides survival benefits.
Related topics: Skin Cancer, Melanoma, Cancer, Medical Research

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Ucla Researchers Find Chronic Inflammation Contributes To Cancer Metastasis

The study reveals a detailed epigenetic mechanism for how interleukin-1-beta, a common cytokine that helps fight infections during inflammation, plays a critical role in cancer metastasis.
Related topics: Medical Research, Cancer, Oncology

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Scientists Identify Protein That Promotes Brain Metastasis

A protein that breast, lung and other cancers use to promote their spread -- or metastasis -- to the brain, has been identified. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent...
Related topics: Proteins, Brain Tumors, Breast Cancer, Lung Cancer, Cancer, Oncology

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Study Unveils The Intricate Way Two Proteins Interact To Promote Cell Movement, Metastasis

When cells in our bodies need to move—to attack an infection or heal a wound, for example—cellular proteins send and receive a cascade of signals that directs the cells to the right place at the right time. It's a process cancer cells can hijack...
Related topics: Medical Research, Proteins, Cancer, Oncology

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New Mechanism Fueling Brain Metastasis

Scientists described a novel mechanism through which astrocytes, the most abundant supporting cells in the brain, also promote cancer cell growth and metastasis in the brain.
Related topics: Brain Tumors, Cancer, Oncology

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New Mechanism Fueling Brain Metastasis Discovered At Wistar

Wistar scientists described a novel mechanism through which astrocytes, the most abundant supporting cells in the brain, also promote cancer cell growth and metastasis in the brain.
Related topics: Brain Tumors, Medical Research, Cancer, Oncology

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Caught In The Act: Proteins Responsible For Metastasis

Research by Assoc. Prof. Nurhan Özlü of Koç University Department of Molecular Biology and Genetics and her team, recently published in Molecular & Cellular Proteomics, has uncovered the effects of two proteins in the transition from the...
Related topics: Proteins, Medical Research, Genetics

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The Path Of Breast-to-brain Cancer Metastasis

Scientists have discovered a signaling pathway that breast tumors exploit to metastasize to the brain.
Related topics: Breast Cancer, Brain Tumors, Cancer, Oncology, Medical Research

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Nanoparticle Therapy Targets Lymph Node Metastases

Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients. The lymph nodes -- glands of the immune system located throughout the body -- are typically the...
Related topics: Lymph Nodes, Cancer, Oncology

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Nanoparticle Therapy Targets Lymph Node Metastases

Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients. The lymph nodes—glands of the immune system located throughout the body—are typically the...
Related topics: Lymph Nodes, Cancer, Oncology

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Crunching The Numbers Of Cancer Metastasis

While revealing that metastatic breast cancer cells alter their shape to spread to other regions of the body, researchers develop a mathematical model that can be applied to study similar cellular systems.
Related topics: Breast Cancer, Cancer, Oncology, Medical Research

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New Alternate Cell Growth Pathway Could Lead To Better Treatments For Metastatic Cancers

A new study has found that the gene, mEAK-7, which they discovered last year, may play a key role in cancer metastasis. By comparing mEAK-7 expression levels in normal and cancer cells, they found that the gene was highly expressed in the cancer...
Related topics: Cancer, Oncology, Medical Research, Genetics

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Active Surveillance Safe For Small Renal Tumors

(MedPage Today) -- Two cases of metastasis, one cancer death among 103 patients after 4+ years of follow-up
Related topics: Cancer, Oncology

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A New Approach To Targeting Tumors And Tracking Their Spread

The spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is the main cause of cancer deaths worldwide. Early detection of tumors and metastases could significantly improve cancer survival rates....
Related topics: Cancer, Oncology

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New Review Identifies Four Hallmarks Of Cancer Metastasis

Researchers have identified four hallmarks of cancer metastasis -- when cancer has spread to different parts of the body from where it started. Metastasis is believed to be the cause of up to 90 percent of cancer deaths.
Related topics: Cancer, Oncology, Medical Research

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Chest Ct May Be Better Than Pet/ct For Hnscc Distant Metastasis Evaluation

MONDAY, March 11, 2019 -- As distant metastasis (DM) in head and neck squamous cell carcinoma (HNSCC) is a rare event, computed tomography of the chest may be more cost-effective for evaluation, according to a study recently published in Oral...
Related topics: Squamous Cell Carcinoma, Medical Research

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The Sneaky Way Estrogen Drives Brain Metastasis In Non-estrogen-dependent Breast Cancers

A new study shows that while estrogen doesn't directly affect triple-negative breast cancer cells, it can affect surrounding brain cells in ways that promote cancer cell migration and invasiveness
Related topics: Estrogen, Brain Tumors, Breast Cancer, Triple Negative Breast Cancer, Cancer, Oncology, Medical Research

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Another Win In Nonmetastatic Crpc

(MedPage Today) -- Novel drug doubles metastasis-free survival, promising for overall survival

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