Multiple Sclerosis

Pregnant Women With Ms Show Increased Nfl

(MedPage Today) -- Serum neurofilament light (NfL) levels rose in women with multiple sclerosis (MS) during pregnancy and postpartum periods when no disease-modifying treatment (DMT) was used, researchers reported. This rise in NfL, a measure...
Related topics: Medical Research

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Clinical Challenges: Test Your Knowledge On Multiple Sclerosis

(MedPage Today) -- A three-question quiz

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Pregnancy May Delay Onset Of Multiple Sclerosis Symptoms

TUESDAY, Sept. 22, 2020 -- Pregnancy is associated with a delay in the onset of multiple sclerosis by more than three years, according to a study published online Sept. 14 in JAMA Neurology. Ai-Lan Nguyen, M.B.B.S., from the Royal Melbourne...
Related topics: Medical Research

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Immune System May Have Another Job — Combatting Depression

An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according to a new Yale-led study...
Related topics: Depression, Medical Research

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Financial Toxicity Common In Patients With Multiple Sclerosis

WEDNESDAY, Sept. 16, 2020 -- For patients with multiple sclerosis (MS), financial toxicity is common and is associated with lifestyle-altering behaviors or care nonadherence, according to a study published online Aug. 18 in the Multiple Sclerosis...
Related topics: Medical Research

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Many Ms Patients Struggle With Finances, Forgo Treatments

TUESDAY, Sept. 15, 2020 -- More than three-quarters of Americans with multiple sclerosis (MS) experience financial difficulties that often prevent them from getting treatment, new research claims. "Our study results demonstrate the high prevalence...
Related topics: Medical Research

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Monthly News Roundup - August 2020

Novartis’ Kesimpta Cleared to Treat Multiple Sclerosis The U.S. Food and Drug Administration (FDA) has approved Kesimpta (ofatumumab), a CD20-directed cytolytic IgG1 antibody used to treat relapsing forms of multiple sclerosis (MS) in...
Related topics: Novartis, Food And Drug Administration

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Risk For Cancer Reduced For Patients With Multiple Sclerosis

FRIDAY, Aug. 28, 2020 -- The risk for cancer is reduced among patients with multiple sclerosis (MS), according to a systematic review and meta-analysis published online Aug. 13 in Autoimmunity Reviews. Mahsa Ghajarzadeh, M.D., M.P.H., from the...
Related topics: Cancer, Oncology

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The First Multiple Sclerosis Patient

Twenty years before Charcot described the nerve-destroying disease multiple sclerosis, an illegitimate British noble spent much of his adult life describing the disease aid its effects.

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Smoking, High Early-life Bmi Projected To Add To Ms Burden

THURSDAY, Aug. 27, 2020 -- The combined estimated multiple sclerosis (MS) population-attributable fractions (PAFs) for smoking and childhood and adolescent high body mass index (BMI) vary from 11 to 14 percent in conservative estimates, according...
Related topics: Smoking

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About One In Three Multiple Sclerosis Patients Have Migraine

WEDNESDAY, Aug. 26, 2020 -- Internationally, more than three in 10 patients with multiple sclerosis (MS) have migraine, according to a review published in the September issue of the Journal of Clinical Neuroscience. Omid Mirmosayyeb, M.D., from...
Related topics: Migraine

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Mechanisms Identified To Restore Myelin Sheaths After Injury Or In Multiple Sclerosis

A research team has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in degenerative diseases. With the insights gained, the researchers were able to regenerate damaged...
Related topics: Medical Research

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Cashews May Hold The Secret To Healing Damaged Nerves

Myelin, the protective sheath that covers nerves, is damaged by certain diseases like multiple sclerosis, leading to chronic pain and, over time, severe dysfunction. Preventing or, in cases where the disease has already progressed, reversing the...
Related topics: Chronic Pain

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Federal Covid-19 Study To Test A Promising Drug Cocktail

Beta interferon, an anti-inflammatory drug that has already been approved for treatment of multiple sclerosis, is being paired with remdesivir in the latest phase of a federal coronavirus trial, The New York Times reports. The remdesivir-focused...
Related topics: Medical Research

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'reelin' In A New Treatment For Multiple Sclerosis

In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease's characteristic symptoms and promoted recovery in symptomatic animals, scientists report.
Related topics: Proteins, Liver Disease

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Relapse Rates Lower With Ofatumumab In Multiple Sclerosis

THURSDAY, Aug. 6, 2020 -- Among patients with relapsing multiple sclerosis, annualized relapse rates are lower for those receiving anti-CD20 monoclonal antibody ofatumumab compared with teriflunomide, according to a study published in the Aug. 6...
Related topics: Medical Research

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Ofatumumab May Beat Older Drug At Preventing Ms Relapse

WEDNESDAY, Aug. 5, 2020 -- A new injection drug can prevent multiple sclerosis flare-ups better than an existing medication, a clinical trial has found. The drug, called ofatumumab, beat a standard MS medication in reducing patients' symptom...
Related topics: Clinical Trials

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Relapses Linked To Accelerated Disability Progression In Spms

TUESDAY, July 28, 2020 -- For patients with secondary progressive multiple sclerosis (SPMS), relapses are associated with accelerated disability progression, according to a study published online July 27 in JAMA Neurology. Nathaniel Lizak,...
Related topics: Medical Research

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Chmp Backs Bupivacaine/meloxicam (zynrelef) For Postop Pain

The CHMPS has recommended granting marketing authorization for the nonopioid drug to treat surgical pain, as well as for a generic form of Fampyra to treat multiple sclerosis associated with walking disability. International Approvals
Related topics: Marketing

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Ms Disease Activity Tied To Comorbidities

(MedPage Today) -- Comorbidities were tied to disease activity in relapsing-remitting multiple sclerosis (MS) patients, a secondary analysis of the CombiRx trial showed. Two comorbidities -- anxiety (HR 1.25, 95% CI 1.01-1.55) and dyslipidemia...
Related topics: Anxiety

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