Osteosarcoma

Minnesota Holder Casey O'brien Says On Twitter He's Survived Cancer For 5th Time

Minnesota walk-on holder Casey O'Brien announced on Twitter that he has survived cancer for the fifth time: Per the Minnesota football team website , O'Brien was diagnosed with osteosarcoma at 13 years old...
Related topics: Social Media, Cancer, Oncology

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Osteosarcoma Profiling Reveals Why Immunotherapy Remains Ineffective

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research.
Related topics: Cancer, Medical Research

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Psoriasis Drug Target Offers Potential For Osteosarcoma

A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings suggest.
Related topics: Psoriasis, Cancer, Oncology

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Genetic Similarities Of Osteosarcoma Between Dogs And Children

A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a new study. The findings could help break the logjam in the treatment of this deadly disease, which hasn't seen a significant medical...
Related topics: Genetics, Bone Cancer, Cancer, Oncology, Medical Research

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Multikinase Inhibitor Extends Pfs In Osteosarcoma

(MedPage Today) -- Accumulating results suggest combination potential for regorafenib

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New Clinical Trials Seek Treatments For Canine Cancers, May Offer Clues On Human Cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors...
Related topics: Clinical Trials, Cancer, Oncology, Medical Research

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Medical News Today: What Is Osteosarcoma?

Osteosarcoma is a type of bone cancer that often affects the shinbone, thighbone, or upper arm. Doctors are currently unsure of the causes, but genetics may play a role. Treatment includes chemotherapy and surgery. The outlook depends on if and how...
Related topics: Bone Cancer, Cancer, Oncology, Genetics, Chemotherapy

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Products Of Omega-3 Fatty Acid Metabolism May Have Anticancer Effects

A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer's growth and spread, researchers report in a new study in mice. In mice with tumors of osteosarcoma - a bone cancer that is notoriously painful and...
Related topics: Bone Cancer, Cancer, Oncology, Medical Research

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Alex Huang, Md, Phd, Receives $450,000 From Pediatric Cancer Research Foundation

Leading cancer researcher, Alex Huang MD, PhD, has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma.
Related topics: Cancer, Oncology, Medical Research

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Scientists Test Nanoparticle Drug Delivery In Dogs With Osteosarcoma

An engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. They chose dogs -- mammals closer in size and biology to humans -- with naturally occurring bone...
Related topics: Bone Cancer, Cancer, Oncology

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New Therapeutic Pathway May Keep Cancer Cells Turned 'off'

A new study offers tangible evidence that it is possible to keep osteosarcoma lesions dormant using novel nanomedicines. Osteosarcoma is a cancer that develops in the bones of children and adolescents. It is one of the most aggressive cancers, with...
Related topics: Bone Cancer, Cancer, Oncology, Medical Research

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Dna Imprinting Defects Associated With Childhood Osteosarcoma Development, Progression

Children diagnosed with osteosarcoma may be impacted by a DNA imprinting defect also found in parents, according to new research. DNA imprinting is a phenomenon in which just one of the two inherited genes is active while the other is present but...
Related topics: DNA, Genetics, Medical Research

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Antibody Developed To Save Cancerous Bones

Osteosarcoma (OS) is a rare cancer most often affecting adolescents and children. While most bone cancers have their origin in other body tissues and spread to the bones through metastases, OS originates in the bone tissue. Researchers now show that...
Related topics: Cancer, Bone Cancer, Oncology, Medical Research

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We Can All Make A Difference.

Kaela Cruz is an unlikely hero who, after being diagnosed with osteosarcoma (bone cancer) at age 4, had to have her left leg amputated above the knee. Since that time Kaela has become an accomplished swimmer, martial artist and has even completed...
Related topics: Bone Cancer, Cancer, Oncology

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Protein Implicated In Osteosarcoma's Spread Acts As Air Traffic Controller

The investigation of a simple protein has uncovered its uniquely complicated role in the spread of the childhood cancer, osteosarcoma. It turns out the protein, called ezrin, acts like an air traffic controller, coordinating multiple functions...
Related topics: Proteins, Air Traffic Control, Cancer, Oncology

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Protein Implicated In Osteosarcoma's Spread Acts As Air Traffic Controller

The investigation of a simple protein has uncovered its uniquely complicated role in the spread of the childhood cancer, osteosarcoma. It turns out the protein, called ezrin, acts like an air traffic controller, coordinating multiple functions...
Related topics: Proteins, Air Traffic Control, Cancer, Oncology

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Potential Proteins Identified To Target In Osteosarcoma Treatment

The genes and pathways that, when altered, can cause osteosarcoma have been identified by researchers using new models. The information could be used to better target treatments for the often-deadly type of cancer.
Related topics: Proteins, Genetics, Medical Research, Cancer, Oncology

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When The Back Pain Red Flags Aren’t Enough

$28 million was awarded to a patient for a late diagnosis of a pelvic tumor, an osteosarcoma. This rare cancer presented as a case of low back pain and sciatica. The patient claimed that if the osteosarcoma had been caught earlier that the...
Related topics: Cancer, Oncology

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Gene Signatures Predict Doxorubicin Response In K9 Osteosarcoma

New work by the University of Colorado Cancer Center presented at AACR 2015 demonstrates a gene expression model that predicts canine osteosarcoma response to doxorubicin, potentially allowing veterinary oncologists to better choose which drug to...
Related topics: Genetics, Medical Research, Cancer, Oncology

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This Dog Is Battling Bone Cancer And Had His Leg Amputated, But He's Still Loving Life

Life has not been easy for this pooch, but it hasn't stopped him from living it up.A short film uploaded to YouTube called "Tri-Pawed: Embracing Canine Osteosarcoma" chronicles the journey of Sheridan, a pup living with his owners, Morgan and Zack...
Related topics: Bone Cancer, Cancer, Oncology

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