Ovarian Cancer

Modest Responses With Immunotherapy Combo For Advanced Ovarian Cancer

(MedPage Today) -- Study Authors: Dmitriy Zamarin, Robert A. Burger, et al. Target Audience and Goal Statement: Oncologists, obstetrician-gynecologists The goal of this study was to evaluate the combination of the programmed death-1 (PD-1)...
Related topics: Cancer, Oncology, Medical Research, Gynecology

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Avelumab Flops Again In Ovarian Cancer

]]>(MedPage Today) -- Another year brings another negative avelumab (Bavencio) trial in ovarian cancer, and more experts are left scratching their heads. In JAVELIN Ovarian 100, median progression-free survival (PFS) for patients who received...
Related topics: Cancer, Oncology

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Coronavirus Reports – Part 3: “i Should Have Known When They Came Back In Ppe”

We caught up with people living with cancer across the country, to find out how the coronavirus pandemic has been affecting them and their families. Christine: “I should have known when they came back in PPE” Christine was diagnosed with ovarian...
Related topics: Cancer, Oncology

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Dual Maintenance Best In Brca-mutant Ovarian Cancer?

]]>(MedPage Today) -- Combination maintenance therapy with bevacizumab (Avastin) plus olaparib (Lynparza) in newly diagnosed, advanced BRCA-associated ovarian cancer may be superior to olaparib alone, a population-adjusted comparison of two phase...
Related topics: Cancer, Oncology, Avastin

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Asco Preview: Boosting Survival In Ovarian Cancer

]]>(MedPage Today) -- Women with relapsed, platinum-sensitive ovarian cancer associated with BRCA mutations lived more than a year longer if they received olaparib (Lynparza) following chemotherapy, data from a randomized trial showed. After...
Related topics: American Society Of Clinical Oncology, Cancer, Oncology, Genetics, Chemotherapy

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Parp Inhibitors Still Work In Hrd-low Ovarian Cancer

]]>(MedPage Today) -- Homologous recombination deficiency (HRD) scoring failed to predict PARP inhibitor response in BRCA wild-type ovarian cancer, as women with low scores still appeared to derive benefit, an exploratory analysis of a phase III...
Related topics: Cancer, Oncology

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Major Trial Shows Breast Cancer Drug Can Hit Prostate Cancer Achilles Heel

A drug already licensed for the treatment of breast and ovarian cancers is more effective than targeted hormone therapy at keeping cancer in check in some men with advanced prostate cancer, a major clinical trial reports. Olaparib, a pill lacking...
Related topics: Clinical Trials, Breast Cancer, Cancer, Prostate Cancer, Oncology, Hormones

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New Standard In Recurrent, Platinum-sensitive Ovarian Cancer

]]>(MedPage Today) -- Replacing gemcitabine (Gemzar) with pegylated liposomal doxorubicin in a standard platinum-based regimen improved survival in recurrent ovarian cancer, a phase III trial has shown. In a cohort of nearly 700 women receiving...
Related topics: Cancer, Oncology

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Breastfeeding May Lower Risk Of Ovarian Cancer

Nursing for three months was associated with an 18 percent lower risk of ovarian cancer, and for more than a year with a 34 percent lower risk.
Related topics: Cancer, Oncology, Nursing

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Checkpoint Combo Tops Single Agent In Advanced Ovarian Cancer

]]>(MedPage Today) -- Dual immune-checkpoint inhibition almost tripled the response rate in patients with advanced ovarian cancer as compared with a single agent, a small randomized trial showed. The overall response rate increased from 12.2%...
Related topics: Cancer, Oncology

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Breastfeeding Tied To Lower Ovarian Cancer Risk

]]>(MedPage Today) -- Breastfeeding for any duration was linked with a reduced risk of borderline and invasive ovarian tumors, a retrospective study indicated. In a pooled analysis of nearly 24,000 women, breastfeeding at any point was...
Related topics: Cancer, Oncology, Medical Research

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Experimental Blood Test Detects Many Dangerous Cancers, Study Finds

The test is designed to find cancers that shed DNA into the blood, including pancreatic and ovarian cancer, says Prof. Geoff Oxnard of Dana-Farber and Harvard, who helped lead the study.
Related topics: Blood Test, DNA Test, Cancer, Pancreatic Cancer, Oncology, Medical Research, DNA, Genetics, Harvard University

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Gene Tests May Guard Older Breast Cancer Patients Against Other Tumors

TUESDAY, March 10, 2020 -- A significant number of older women with breast cancer may have genetic mutations that put them at risk of additional cancers, particularly ovarian cancer, a new study finds. The researchers said that as many as one in...
Related topics: Genetics, Breast Cancer, Cancer, Oncology, Medical Research

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Oncologists Are 'sacrificing Common Sense' In Pursuit Of Innovation

Dr Bishal Gyawali on how reaction to a recent ovarian cancer study reveals a troubling trend among oncologists of doubting negative results. Medscape Oncology
Related topics: Cancer, Oncology, Medical Research

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Here's Why Clovis Oncology Has Upside Potential In 2020

Cancer drug maker Clovis Oncology (NASDAQ: CLVS) has seen tremendous growth recently, with the stock up more than 57% in the past six months. The 11-year-old company is developing targeted therapies in various cancers including ovarian cancer,...
Related topics: Cancer, Oncology, Prostate Cancer, Nasdaq

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News Digest – Smoke-free 2030, Electronic Noses, Ovarian Cancer And The Microbiome

England unlikely to meet government’s 2030 smoke-free target Last year, the Government set a target to make England smoke-free by 2030. But the ambitious target is unlikely to be realised until the Government tackles smoking in some of the most...
Related topics: Smoking, Cancer, Oncology, Microbiome

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The Making Of A Living Ovarian Cancer Biobank

It’s an ordinarily overcast day, but the artificial lights of the lab radiate a crude brightness for Professor Stephen Taylor and his team. The room is bustling and busy. Scientific equipment and bottles filled with striking liquids are spread...
Related topics: Cancer, Oncology

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Scientists Identify Protein Associated With Ovarian Cancer That Exacerbates Neurodegeneration In...

Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer's disease, by combining computational methods and lab research.
Related topics: Proteins, Brain Tumors, Cancer, Oncology, Alzheimer's Disease, Medical Research

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Medical News Today: Does Talc Powder Cause Ovarian Cancer?

Scientists using the largest data set yet saw no link between powder use in the genital area and ovarian cancer. But they urge caution.
Related topics: Cancer, Oncology

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Medical News Today: Through My Eyes: Surviving Cancer Twice

In 1972, I survived breast cancer only to receive a diagnosis of stage 4 ovarian cancer in the following decade. This is my story.
Related topics: Breast Cancer, Cancer, Oncology

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