Placebo

New Insight Into How Cannabidiol Takes Effect In The Brains Of People With Psychosis

Published in Psychological Medicine, the research used fMRI scans to examine the brain activity of 13 people with a diagnosis of psychosis under the influence of a single dose of CBD or placebo and 16 controls whilst they were undertaking a memory...
Related topics: Psychology, Medical Research

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Claims About Placebos

…the placebo effect in the United States has actually become quite a lot stronger over time, meaning that drugs that once would have been approved may not be now – because their performance relative to that of placebo is less convincing....

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In Children With Multiple Sclerosis, Teriflunomide Tempers Lesion Growth

A phase 3 clinical trial tested the safety and efficacy of teriflunomide, an oral immunomodulatory drug, in children with multiple sclerosis. Although the medication did not prevent disease relapses to a greater extent than placebo, the option for...
Related topics: Multiple Sclerosis, Clinical Trials

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Platelet-rich Plasma Injections Show No Benefit In Knee Oa

Platelet-rich plasma injections for mild to moderate knee osteoarthritis (OA) show no improvements in pain, function, or cartilage structure, compared with placebo. Medscape Medical News
Related topics: Arthritis, Osteoarthritis, Cartilage

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Secukinumab Sustained Remission Of Gca After Steroid Taper

There was a substantial effect size for secukinumab vs placebo in sustaining remission for patients with giant cell arteritis, but a steroid-tapering protocol likely amplified the effect. Medscape Medical News

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Expectations And Dopamine Can Affect Outcome Of Ssri Treatment

Levels of dopamine and the placebo effect can determine whether patients with social anxieties improve when treated with SSRIs.
Related topics: Selective Serotonin Reuptake Inhibitors

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Risankizumab Outperforms Placebo At 6 Months For Psoriatic Arthritis

At the 24-week assessment, participants receiving risankizumab showed greater improvement in primary and secondary endpoints than did placebo with no new safety signals. Medscape Medical News
Related topics: Psoriatic Arthritis, Arthritis

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Pfizer (pfe) Covid Pill Shows Strong Efficacy, Stock Rallies

Pfizer’s PFE oral antiviral candidate for COVID-19, Paxlovid reduced the risk of hospitalization or death by 89% compared to placebo in an interim analysis of a phase II/III study.The study, EPIC-HR, was conducted on non-hospitalized adult...
Related topics: Pfizer, Medical Research

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Rituximab Improves Systemic Sclerosis Skin, Lung Symptoms

Patients who took rituximab in the DESIRES trial had better skin scores and lung function at 6 months than did patients who received placebo. Medscape Medical News

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Early Success With New Target In Atopic Dermatitis

(MedPage Today) -- NEW YORK CITY -- An oral drug that targets Th2 activity in atopic dermatitis reduced disease activity by as much as 50% after 6 weeks, results of a small placebo-controlled study showed. At 4 weeks of treatment with RPT193...
Related topics: Dermatitis, Medical Research

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Pfizer: Antiviral Pill Reduces Coronavirus Death, Hospitalization In High-risk Patients By 89...

Pfizer announced on Friday that its antiviral COVID-19 pill cut the risk of coronavirus hospitalizations and deaths by 89 percent compared to those who received a placebo, according to an analysis of study data.In a study examining adults who had...
Related topics: Pfizer, Medical Research

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Liraglutide After Gastric Bypass Helped Stave Off Weight Regain

(MedPage Today) -- Taking the GLP-1 receptor agonist liraglutide (Saxenda) might help bariatric surgery patients maintain weight loss, a double-blind, placebo-controlled study suggested. In patients who had successfully lost at least 25% of their...
Related topics: Medical Research

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Novel Oral Antidepressant Shows Rapid Symptom Improvement

(MedPage Today) -- A 2-week oral treatment for major depressive disorder was both safe and effective, according to the phase III WATERFALL study. Compared with placebo, adults treated with zuranolone, an investigational neuroactive steroid and...
Related topics: Depression, Antidepressants, Medical Research

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Monoclonal Antibody Treatment Highly Effective At Reducing Covid-19 Hospitalizations

Researchers published interim results in The New England Journal of Medicine from a Phase 3 study of the COVID-19 monoclonal antibody treatment sotrovimab, sponsored by Vir Biotechnology and GlaxoSmithKline. The study found that compared to the...
Related topics: Medical Research, Biotechnology, GlaxoSmithKline

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No Love For Prp In Ankle Osteoarthritis Trial

(MedPage Today) -- Patients with ankle osteoarthritis got no more relief from platelet-rich plasma (PRP) injections than placebo shots in a randomized, double-blind trial in The Netherlands. Six months after the participants received two...
Related topics: Arthritis, Osteoarthritis

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Relugolix Side Effects In Fibroids, Endometriosis May Be Minimal

Headache and hot flush occurred at similar rates with relugolix combination therapy or placebo, a study shows. Medscape Medical News
Related topics: Medical Research

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Pan-ppar Agonist 'promising' For Nash Patients

(MedPage Today) -- Patients with active nonalcoholic steatohepatitis (NASH) who received the investigational oral drug lanifibranor (IVA337) showed greater reduction in disease activity compared to placebo, a randomized phase IIb trial found....

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Laser Therapy For Vaginal Rejuvenation

Some doctors are offering laser therapy for "vaginal rejuvenation". It is no more effective than placebo, can cause harm, and is very expensive. The post Laser Therapy for Vaginal Rejuvenation first appeared on Science-Based Medicine.

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Virtual Museums Challenge The Art World’s Status Quo

Lack of access to physical galleries opened people’s eyes to digital possibilities. Will they revolutionize how we interact with art—or just be a placebo?
Related topics: Museum

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Astrazeneca Says Covid-19 Drug Helps Cut Risk Of Severe Disease, Death

AstraZeneca announced on Monday that its experimental COVID-19 treatment has been found to be effective in late-stage trials at preventing severe illness or death.When compared to a placebo, AstraZeneca's antibody treatment, called ...
Related topics: Astrazeneca

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