Published in Psychological Medicine, the research used fMRI scans to examine the brain activity of 13 people with a diagnosis of psychosis under the influence of a single dose of CBD or placebo and 16 controls whilst they were undertaking a memory...
Related topics: Psychology, Medical Research
…the placebo effect in the United States has actually become quite a lot stronger over time, meaning that drugs that once would have been approved may not be now – because their performance relative to that of placebo is less convincing....
A phase 3 clinical trial tested the safety and efficacy of teriflunomide, an oral immunomodulatory drug, in children with multiple sclerosis. Although the medication did not prevent disease relapses to a greater extent than placebo, the option for...
Related topics: Multiple Sclerosis, Clinical Trials
Platelet-rich plasma injections for mild to moderate knee osteoarthritis (OA) show no improvements in pain, function, or cartilage structure, compared with placebo. Medscape Medical News
Related topics: Arthritis, Osteoarthritis, Cartilage
There was a substantial effect size for secukinumab vs placebo in sustaining remission for patients with giant cell arteritis, but a steroid-tapering protocol likely amplified the effect. Medscape Medical News
Levels of dopamine and the placebo effect can determine whether patients with social anxieties improve when treated with SSRIs.
Related topics: Selective Serotonin Reuptake Inhibitors
At the 24-week assessment, participants receiving risankizumab showed greater improvement in primary and secondary endpoints than did placebo with no new safety signals. Medscape Medical News
Related topics: Psoriatic Arthritis, Arthritis
Pfizer’s PFE oral antiviral candidate for COVID-19, Paxlovid reduced the risk of hospitalization or death by 89% compared to placebo in an interim analysis of a phase II/III study.The study, EPIC-HR, was conducted on non-hospitalized adult...
Related topics: Pfizer, Medical Research
Patients who took rituximab in the DESIRES trial had better skin scores and lung function at 6 months than did patients who received placebo. Medscape Medical News
(MedPage Today) -- NEW YORK CITY -- An oral drug that targets Th2 activity in atopic dermatitis reduced disease activity by as much as 50% after 6 weeks, results of a small placebo-controlled study showed.
At 4 weeks of treatment with RPT193...
Related topics: Dermatitis, Medical Research
Pfizer announced on Friday that its antiviral COVID-19 pill cut the risk of coronavirus hospitalizations and deaths by 89 percent compared to those who received a placebo, according to an analysis of study data.In a study examining adults who had...
Related topics: Pfizer, Medical Research
(MedPage Today) -- Taking the GLP-1 receptor agonist liraglutide (Saxenda) might help bariatric surgery patients maintain weight loss, a double-blind, placebo-controlled study suggested.
In patients who had successfully lost at least 25% of their...
Related topics: Medical Research
(MedPage Today) -- A 2-week oral treatment for major depressive disorder was both safe and effective, according to the phase III WATERFALL study.
Compared with placebo, adults treated with zuranolone, an investigational neuroactive steroid and...
Related topics: Depression, Antidepressants, Medical Research
Researchers published interim results in The New England Journal of Medicine from a Phase 3 study of the COVID-19 monoclonal antibody treatment sotrovimab, sponsored by Vir Biotechnology and GlaxoSmithKline. The study found that compared to the...
Related topics: Medical Research, Biotechnology, GlaxoSmithKline
(MedPage Today) -- Patients with ankle osteoarthritis got no more relief from platelet-rich plasma (PRP) injections than placebo shots in a randomized, double-blind trial in The Netherlands.
Six months after the participants received two...
Related topics: Arthritis, Osteoarthritis
Headache and hot flush occurred at similar rates with relugolix combination therapy or placebo, a study shows. Medscape Medical News
Related topics: Medical Research
(MedPage Today) -- Patients with active nonalcoholic steatohepatitis (NASH) who received the investigational oral drug lanifibranor (IVA337) showed greater reduction in disease activity compared to placebo, a randomized phase IIb trial found....
Some doctors are offering laser therapy for "vaginal rejuvenation". It is no more effective than placebo, can cause harm, and is very expensive.
The post Laser Therapy for Vaginal Rejuvenation first appeared on Science-Based Medicine.
Lack of access to physical galleries opened people’s eyes to digital possibilities. Will they revolutionize how we interact with art—or just be a placebo?
Related topics: Museum
AstraZeneca announced on Monday that its experimental COVID-19 treatment has been found to be effective in late-stage trials at preventing severe illness or death.When compared to a placebo, AstraZeneca's antibody treatment, called ...
Related topics: Astrazeneca