Stem Cells

Researchers Regrow Damaged Nerves With Polymer And Protein

Researchers have created a biodegradable nerve guide -- a polymer tube -- filled with growth-promoting protein that can regenerate long sections of damaged nerves, without the need for transplanting stem cells or a donor nerve.
Related topics: Medical Research, Proteins

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Snake Stem Cells Used To Create Venom-producing Organoids

Organoids have become an important tool for studying many disease processes and testing potential drugs. Now, they are being used in a surprising and unexpected way: for the production of snake venom. On January 23 in the journal Cell, researchers...
Related topics: Medical Research

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Solving A Biological Puzzle: How Stress Causes Gray Hair

Scientists have found evidence to support long-standing anecdotes that stress causes hair graying. Researchers found that in mice, the type of nerve involved in the fight-or-flight response causes permanent damage to the pigment-regenerating stem...
Related topics: Stress, Medical Research

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Multivariate Patterning Of Human Pluripotent Cells Reveals Induced Paracrine Factors In Kidney...

Bioengineers have shown great promise in creating complex multicellular kidney organoids (tiny, self-organized tissues) in the lab using pluripotent stem cells . They can further improve the procedure for different outcomes, including patterning...

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Gains In Stem Cell Transplant Mortality Over Last 25 Years

]]>(MedPage Today) -- Outcomes have improved over the last quarter-century for patients undergoing allogeneic hematopoietic cell transplantation for treating their cancer, a single-center cohort study indicated. Reported in the Annals of Internal...
Related topics: Cancer, Oncology, Medical Research

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Isscr Statement On Ethical Standards For Stem Cell-based Embryo Models

The ISSCR is updating its Guidelines for Stem Cell Research and Clinical Translation to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell...
Related topics: Medical Research

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Cancer Study May Accidentally Help Researchers Create Usable Blood Stem Cells

University of Colorado Cancer Center study shows healthy form of the leukemia-causing gene MLL may push pluripotent stem cells (which have proven difficult to use in human patients) to become durable hematopoietic stem cells (which are usable in...
Related topics: Cancer, Oncology, Medical Research, Leukemia, Genetics

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Neurologist Copes With Alzheimer's; Stem Cells Vs Biologics In Ms

]]>(MedPage Today) -- In the wake of recent New York Times articles, a neurologist with early Alzheimer's and others wrote letters to the editor about coping with the disease. WHO formally retracted its two main opioid guidelines after a review...
Related topics: Alzheimer's Disease

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Blood Stem Cell Research

A nanoparticle carrier system that could eliminate the need for bone marrow transplants, which are both expensive and difficult for patients to undergo. The University of Delaware's Emily Day, an assistant professor of biomedical engineering, is...
Related topics: Medical Research

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Artificial Muscle Sheets Transform Stem Cells Into Bone

Specifically programmed materials can, under specific conditions, encourage stem cells to transform into bone cells. To do this, scientists implemented a so-called shape-memory polymer in stem cell research.
Related topics: Medical Research

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A Simple Twist Of Cell Fate

How do a couple of universally expressed proteins in stem cells and developing embryos influence an individual cell's ultimate fate—whether it ultimately becomes, for example, a retinal cell, a heart muscle cell, or a stomach lining cell?
Related topics: Proteins

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"scientists Use Stem Cells From Frogs To Build First Living Robots."

The Guardian reports.One of the most successful creations has two stumpy legs that propel it along on its “chest”...Roboticists tend to favour metal and plastic for their strength and durability, but Levin and his colleagues see benefits in...
Related topics: Robots

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New Protocol To Generate Intestinal Organoids In Vitro

Researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system. Using human induced pluripotent stem...
Related topics: Medical Research

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First Genomic Study Of Puberty Yields Insights Into Development And Cancer

In the first-ever genome-scale analysis of the puberty process in humans, researchers outline distinct and critical changes to stem cells in males during adolescence.
Related topics: Genetics, Genomics, Medical Research, Cancer, Oncology

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Rejuvenating The Brain With Stem Cells

The older we get the more our brains will find it difficult to learn and remember new things. The research group used a method to stimulate the small pool of neural stem cells that reside in the brain in order to increase their number and the number...
Related topics: Medical Research

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Untreated Oral Infection Not Tied To Stem Cell Transplant Outcomes

THURSDAY, Jan. 9, 2020 -- Untreated chronic oral infection is not associated with post-hematopoietic stem cell transplant (HSCT) outcomes, according to a study published online Dec. 18 in PLOS ONE. Matti Mauramo, D.D.M., from the University of...
Related topics: Medical Research

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Researchers Unveil Stem Cell Models Of Human Spine Development

More than 20 years ago, the lab of developmental biologist Olivier Pourquié discovered a sort of cellular clock in chicken embryos where each “tick” stimulates the formation of a structure called a somite that ultimately becomes a vertebra....
Related topics: Medical Research

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Plant-derived Svc112 Hits Cancer Stem Cells, Leaves Healthy Cells Alone

Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow
Related topics: Cancer, Oncology, Medical Research, Proteins

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Aspirin Can Help Stem The Tide Of Stroke. Why Aren’t More Doctors Prescribing It?

First sold commercially 119 years ago, aspirin is a remarkable drug. Cheap and with few side effects, its benefits include the ability to prevent blood cells from clotting. As a result, it’s given to patients who have suffered heart attacks,...
Related topics: Aspirin, Stroke

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Lab-grown Mini Brains Could Soon Outsmart Us

The cutting-edge method of growing clusters of cells that organize themselves into mini versions of human brains in the lab is gathering more and more attention. These “brain organoids,” made from stem cells, offer unparalleled insights into the...

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