Tuberculosis

Medical News Today: Self-destruction System In Tb Bacteria May Lead To 'perfect Drug'

Scientists zoom in on the 'toxin-antitoxin' system that the tuberculosis bacterium naturally contains, in the hope that it can help design better drugs.
Related topics: Bacteria

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Suicide System In Tuberculosis Bacteria Might Hold Key To Treatment

Tuberculosis (TB) is one of the top ten causes of death worldwide. In 2017, 10 million people around the world fell ill with TB and 1.3 million died. The genome of the bacterium that causes TB holds a special toxin-antitoxin system with spectacular...
Related topics: Bacteria, Genetics

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Tuberculosis: Commandeering A Bacterial 'suicide' Mechanism

The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The scientists are now seeking to appropriate this 'suicide' mechanism for therapeutic purposes.
Related topics: Bacteria, Antidote, Proteins

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Stopping The World's Biggest Infectious Killer

Science holds the key for ending tuberculosis, but greater effort and sustained innovation are crucial -- Read more on ScientificAmerican.com

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Worldwide, More Die After Surgery Than From Hiv, Malaria: Study

FRIDAY, Feb. 8, 2019 -- About 4.2 million people worldwide die every year within 30 days of surgery -- more than from HIV, tuberculosis and malaria combined, a new study reports. The findings show that 7.7 percent of all deaths worldwide occur...
Related topics: HIV, Virus, Malaria, Medical Research

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Assessing The Airborne Survival Of Bacteria In Aerosol Droplets From Coughs And Sneezes

The airborne transmission of diseases including the common cold, influenza and tuberculosis is something that affects everyone with an average sneeze or cough sending around 100,000 contagious germs into the air at speeds of up to 100 miles per hour.
Related topics: Bacteria, Influenza (Flu), Cough, Germs

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The Gates Foundation Has Given Nearly $10 Billion To These Four Organizations

Since 1999, the Bill & Melinda Gates Foundation has given close to $10 billion to four public health organizations. The four are: Gavi, focused on childhood vaccines the Global Polio Eradication Initiative the Global Fund to Fight AIDS,...
Related topics: Bill Gates, Vaccines

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Genetic Mutation Responsible For Tuberculosis Vulnerability

Scientists discovered a genetic variant that greatly increases a person's likelihood of developing tuberculosis. Their research elucidates how this mutation affects the immune system, and points to a possible treatment for people with the disease.
Related topics: Genetics, Medical Research

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Nearly One In Five Tibetan Refugee Schoolchildren Has Tuberculosis Infection, Study Finds

In a tuberculosis screening and treatment initiative covering the entire population of Tibetan refugee schoolchildren in northern India, a team of researchers says it has found not only a startlingly high prevalence of TB disease and infection, but...
Related topics: Medical Research

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With A Focus On High-risk Patients, Researcher Eyes Eliminating Tb For Good

A focus on high-risk tuberculosis patients may be the answer to stalled progress in stamping out the illness in the United States.
Related topics: Medical Research

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Lung Lavage As New Test Method Improves Tuberculosis Diagnosis In Rhinoceros

Scientists performed repeated lung lavage as a new approach for tuberculosis diagnosis in rhinoceros. Subsequent genetic tests reliably identified mycobacteria in the animals' respiratory fluids -- with minimal stress and risk for the rhinos.
Related topics: Genetics, Stress

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Illegal Medicines May Be Making India’s Tuberculosis And Malaria Crises Worse

India is awash with unapproved drug formulations, including those dispensed for diseases like TB and malaria, raising safety and efficacy concerns, says a new study. India is called the “pharmacy to the world” for its massive production...
Related topics: Malaria, Medical Research

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Migrant Caravan Suffering Mass Outbreaks Of Tuberculosis, Skin Infections

The caravan stopped in the Mexican city of Tijuana, not far from the desired US border, waiting for their asylum applications to be processed by American authorities - but only after some migrants tried to rush their way through the fence by force.

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Structural Study Of Antibiotic Opens The Way For New Tb Treatments

New analysis of the structure and function of the naturally-occurring antimicrobial agent tunicamycin has revealed ways to produce new, safe antibiotics for Mycobacterium tuberculosis and other disease-causing bacteria.
Related topics: Medical Research, Antibiotics, Bacteria

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Stratifying By Severity May Allow Shorter Tb Tx Regimens

TUESDAY, Nov. 6, 2018 -- Stratifying tuberculosis (TB) patients by disease severity may enable shorter treatment regimens, according to a study published online Nov. 5 in Nature Medicine. Marjorie Z. Imperial, from the University of California at...
Related topics: Medical Research

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Movement, Evolutionary History Of Tuberculosis In China

A genetic scan of a massive number of samples taken from tuberculosis patients across China has shown a surprising genetic uniformity: just two 'strains' of the tuberculosis bacterium account for 99.4 percent of all cases.
Related topics: Genetics

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Drugs From Dirt

Analyzing soil samples from across the country, researchers have identified an antibiotic capable of treating strains of tuberculosis that do not respond to existing therapies.
Related topics: Medical Research, Antibiotics

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Searching In Soil, Scientists Find A New Way To Combat Tuberculosis

For decades, doctors have been using antibiotics to fight tuberculosis (TB). And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic...
Related topics: Antibiotics

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European Colonizers Likely Spread Tuberculosis To The Rest Of The World

European colonizers could be to blame for bringing tuberculosis to other parts of the world. tuberculosis is one of the most serious health issues worldwide killing 1.6 million people per year. In a new study published in Science Advances on...
Related topics: Medical Research

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European Badgers' Gut Bacteria May Be A Powerful Ally In The Fight Against Tuberculosis

What do cattle, European badgers, and gut bacteria have in common? They are all central players in a complex web surrounding a disease that affects multiple species, often with devastating results—tuberculosis. Now, new research funded by Morris...
Related topics: Bacteria, Medical Research

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