Proteins

Genetic Signature Boosts Protein Production During Cell Division

A research team has uncovered a genetic signature that enables cells to adapt their protein production according to their state. The researchers of the University of Basel's Biozentrum report in Genome Biology that this newly discovered mechanism...
Related topics: Genetics, Scientific Discoveries

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The Viral Test

This is the editor’s letter in the current issue of The Week magazine. Viruses, strictly speaking, are not alive. They are tiny sets of genes bundled within protein shells, with one singular function — to replicate. Lacking cells or other common...
Related topics: Virus, Virology, Genetics

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New Technique Could Streamline Drug Design

Researchers have developed a process that could sharply reduce the work involved in computational protein design, according to a study in Proceedings of the National Academy of Sciences.
Related topics: Medical Research

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How Enzymes Build 'sugar Trees'

Researchers have used cryo-electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees that are subsequently attached to other membrane...
Related topics: Electrons

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Scientists Create Solar Panel By Combining Protein And Quantum Dots

Scientists at the National Research Nuclear University MEPhI (Russia) have created a new type of solar panel based on hybrid material consisting of quantum dots (QDs) and photosensitive protein. The creators believe that it has great potential for...
Related topics: Quantum, Physics

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Researchers Make Asthma-caspase-11 Breakthrough

Researchers from Trinity College Dublin have made a breakthrough that may eventually lead to improved therapeutic options for people living with asthma. The researchers have uncovered a critical role for a protein (Caspase-11), which had previously...
Related topics: Medical Research, Asthma

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Microrna Regulates Process Vital To Placenta Growth In Early Pregnancy

Researchers have discovered how a very large human non-protein coding gene regulates epithelial-to-mesenchymal transition (EMT) -- a process that contributes to placental implantation during early pregnancy, as well as cancer progression and spread....
Related topics: MicroRNA, Medical Research, Genetics, Cancer, Oncology

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Too Much Of A Good Thing May Lead To Too Much Of A Liver As Well

Researchers suggest that prolonged exposure to a pair of antioxidant proteins may contribute to enlargement of the liver and fatty liver diseases.
Related topics: Medical Research

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Researchers Id Protein Function In Parasites That Cause Sometimes Fatal Diseases

In the quest to develop more effective treatments for parasitic diseases like African sleeping sickness, Chagas disease and Leishmaniasis, scientists look for weaknesses in the organisms' molecular machinery. These weaknesses can then be targeted...
Related topics: Medical Research, Parasites

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Transport Protein Efficiently Uses Three Independent Lifts To Shuttle The Goods

The structure of a transport complex used by bacteria to import aspartate has been mapped in unique detail by University of Groningen scientists. The proteins were imaged using cryo-electron microscopy. The results reveal that the transporter works...
Related topics: Electrons

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Ancient Origins Of Allosteric Activation In The Oldest Kinases

One of the key features in the evolution of more complex organisms is the emergence of allosteric regulation. Allostery is a process by which a protein's activity can be modulated by binding an effector molecule distal to the active site.

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A Chemist Investigates How Proteins Assume Their Shape

When proteins are first made in our cells, they often exist as floppy chains until specialized cellular machinery helps them fold into the right shapes. Only after achieving this correct structure can most proteins perform their biological...

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Abnormally Low Levels Of Key Protein In Brains Of Young Men With Autism

Using cutting-edge imaging technology, researchers at Massachusetts General Hospital (MGH) have shown that the brains of young men with autism spectrum disorder (ASD) have low levels of a protein that appears to play a role in inflammation and...
Related topics: Autism, Medical Research

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Brain Cells Protect Muscles From Wasting Away

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us...
Related topics: Alzheimer's Disease

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Weekly Link Love – Edition 69

Research of the Week Walking isn’t enough to prevent weight gain. Whey protein isolate beats even the most “optimized” blend of plant proteins. The standard Western diet damages memory. An estimation of “post-treatment Lyme...
Related topics: Medical Research, Diet

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Sneaking Up On Tiny Crystals With Electron Diffraction

Understanding the structure of proteins, the building blocks of life, is essential to obtain insight into their biological function. Due to their minute size and extreme fragility, these structures are enormously difficult to determine. Acquiring...
Related topics: Electrons

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The Strategy Of Cells To Deal With The Accumulation Of Misfolded Proteins Is Identified

A new article by the Oxidative Stress and Cell Cycle research group at UPF identifies the main strategy of cells to deal with the accumulation of misfolded proteins. In the paper, published today in the journal Cell Reports, the Schizosaccharomyces...
Related topics: Stress, Medical Research

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Researchers Map Structure Of Coronavirus "spike" Protein

The finding could help lay the groundwork for a vaccine -- Read more on ScientificAmerican.com

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Dna-tagging Strategy For Early Detection Of Disease Signatures

Researchers can uncover how proteins interact with other proteins with far greater sensitivity and in a more natural context than conventional methods, thanks to an analytic technique developed by a RIKEN team. This will make it easier to discover...
Related topics: DNA, Genetics, Medical Research

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Not Fasting Is Killing Us, But Fasting Can Hurt Us Too. Here's What To Do.

There's a switch inside every cell in your body. Flip it on and you're in growth mode. Your cells start dividing — but in the process, they make a lot of junk like mis-folded proteins, which help create the conditions for our biggest diseases...

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