Proteins

New Tools Catch And Release Molecules At The Flip Of A Light Switch

A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly control processes inside...

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How A Protein Stops Cells From Attacking Their Own Dna

Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway. The protein cyclic GMP-AMP Synthase (cGAS), which is also found...
Related topics: DNA, Genetics, Virus, Virology

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Busting Up The Infection Cycle Of Hepatitis B

Researchers have gained new understanding of the virus that causes hepatitis B and the 'spiky ball' that encloses its genetic blueprint. They looked at how the capsid -- a protein shell that protects the blueprint and also drives the delivery of it...
Related topics: Hepatitis, Hepatitis B, Medical Research, Virus, Virology, Genetics

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Unlocking How Cellular Proteins Control Cancer Spread

A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. A McGill-led study reveals key biochemical processes that advance our understanding of colorectal cancer, the third...
Related topics: Cancer, Colon Cancer, Colorectal Cancer, Oncology, Medical Research

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An Animation Visualizing How Amino Acids Build Protein

Scientist Dan Munro partnered with filmmaker Jin Angdoo to create a short but adorable animation that visualizes how a string of amino acids come together in order to sequence a protein. A short film made with a scientist Dan Munro about Protein...

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Unexpected Role Of Two Lipid-binding Mitochondrial Proteins Associated With Heart Disease And...

Mitochondria are the powerhouse of cells, continuously converting energy from food into the chemical energy currency called ATP. This essential process depends on large protein complexes within the inner membrane of mitochondria acting similar to...
Related topics: Cardiovascular Disease, Diabetes

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Protein Uses Two Antiviral Strategies To Ward Off Infections

To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study shows.
Related topics: Virus, Virology, HIV, Medical Research

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Recipe For Success -- Interaction Proteomics Become A Household Item

A research team introduces a new optimized and integrated interaction proteomics protocol that combines two state-of-the art methods to allow rapid identification of protein-protein interactions and more.

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Right Under Your Nose: A More Convenient Way To Diagnose Alzheimer's Disease

Scientists discover a new way to diagnose Alzheimer's disease by analyzing the levels of specific proteins in nasal discharge. This simple and inexpensive method could help in timely diagnosis of Alzheimer's disease, in order to start treatment as...
Related topics: Alzheimer's Disease, Medical Research

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Immunotherapy-resistant Cancers Eliminated In Mouse Study

In a mouse study, researchers have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.
Related topics: Cancer, Oncology, Medical Research

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Researchers Find Clues To Clarify Why Cohesine Has A Role In Cancer And Cardiac Development

Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that is essential in cell division. Losada has studied cohesin since she identified it in vertebrates in 1998, at...
Related topics: Medical Research, Cancer, Oncology

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Research Exposes New Vulnerability For Sars-cov-2

Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus' infamous spike protein—illuminating a relatively simple, potential treatment pathway.
Related topics: Medical Research

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Gluten In Wheat: What Has Changed During 120 Years Of Breeding?

In recent years, the number of people affected by celiac disease, wheat allergy or gluten or wheat sensitivity has risen sharply. But why is this the case? Could it be that modern wheat varieties contain more immunoreactive protein than in the past?...
Related topics: Allergies

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For Bacteria, A Small Genome Means Some Serious Decluttering—even In The Ribosome

Researchers from Skoltech, Lomonosov Moscow State University and the Kharkevich Institute for Information Transmission Problems have studied the genomes of some 200 strains of bacteria to determine which proteins in the ribosome, part of the key...
Related topics: Genetics

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Researchers Identify A Protein That May Help Sars-cov-2 Spread Rapidly Through Cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the...
Related topics: Medical Research, Virus, Virology

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Diets High In Plant Proteins Associated With Lower Mortality Rates - Study

Diets high in plant proteins are associated with lower mortality rates, according to a new study published in medical journal The BMJ.
Related topics: Medical Research

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Imaging Method Highlights New Role For Cellular 'skeleton' Protein

While your skeleton helps your body to move, fine skeleton-like filaments within your cells likewise help cellular structures to move. Now, researchers have developed a new imaging method that lets them monitor a small subset of these filaments,...

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Detailed Molecular Workings Of A Key System In Learning And Memory Formation

Biochemists report how they used advanced sequencing technology to clear up uncertainty and determine all variants of a single protein/enzyme known as calcium/calmodulin-dependent protein kinase II (CaMKII) in the hippocampus, the brain's memory...

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Strong Link Found Between Abnormal Liver Tests And Poor Covid-19 Outcomes

Researchers at the Yale Liver Center found that patients with COVID-19 presented with abnormal liver tests at much higher rates than suggested by earlier studies. They also discovered that higher levels of liver enzymes — proteins released...
Related topics: Medical Research, Enzymes

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Novavax Partners With Takeda To Sell Its Coronavirus Vaccine In Japan

Novavax (NASDAQ: NVAX) is teaming up with Japanese drug maker Takeda Pharmaceutical (NYSE: TAK) to sell Novavax's coronavirus vaccine, NVX-CoV2373, as a prevention for COVID-19 in Japan.Takeda will be responsible for manufacturing the protein...
Related topics: Vaccines, Nasdaq

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